Linfoma não Hodgkin e doença de Hodgkin - Complicação ou associação?
Palavras-chave:
doença de Hodgkin, linfoma não Hodgkin, Linfoma composto, linfoma simultâneo, Linfoma sequencialResumo
O aparecimento de Linfoma não Hodgkin em doentes tratados anteriormente por doença de Hodgkin é um evento descrito e cuja a explicação se baseia num défice imunológico iatrogénico.
Os autores descrevem o caso de um doente de 60 anos, com o diagnóstico de doença de Hodgkin ( escleronodular) em que, durante o tratamento (MOPP), eclode um sindrome da veia cava superior, com proliferação explosiva de adenopatias medianísticas e cervicais cuja histologia revelou Línfoma não Hodgkin de fenótipo B de alto grau de malignidade.
A partir deste caso, aborda-se a possibilidade de associação directa destas patologias, baseada num apatogenia comum.
Os autores concluem da evidência desta associação no caso descrito, bem como da necessidade de repensar os conceitos actualmente consagrados.
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Este trabalho encontra-se publicado com a Licença Internacional Creative Commons Atribuição 4.0.
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