Yersinia enterocolitica bacteraemia and hemochromatosis – Case report

Authors

  • Paulo Ferreira Gouveia Serviço de Medicina 1, Hospital de São Marcos – Braga
  • Vera Costa Dias Serviço de Medicina 1, Hospital de São Marcos – Braga
  • Guilherme Castro Gomes Serviço de Medicina 1, Hospital de São Marcos – Braga

Keywords:

liver abcess, hemochromatosis, Yersinia enterocolitica

Abstract

The authors present a case of a patient with 66 years old, admitted
for fever, diaphoresis, myalgia, mental obtundation and pain in the
right hypochondriac area, with two weeks duration. The imagiologic study of the liver, shows a mycronodular pattern suggestive of
abcedation. Yersinia enterocolitica grows in the hemocultures. The
analytic panel shows a gross alteration of the iron metabolism,
and the histopathology of the liver gave a picture of cirrhosis and
stage 4 siderosis, pointing to the coexistence of hemochromatosis,
verified to be genetically determined by C282Y mutation of the
HFE gene. The patient was treated with a sequence of antibiotics,
including a quinolone, progressing with a sustained but protracted
clinical and radiological resolution, without reinfection or late
complications. To the comments to the case, a brief review of
the septicaemia and liver abscess by the yersinia enterocolitica,
in the overload iron states, is added.

Downloads

Download data is not yet available.

References

Cover TL, Aber RC. Yersinia enterocolitica. N Eng J Med 1989; 321:16-24.

Vantrappen G, Geboes K, Ponette E. Yersinia enteritis. Med Clin North Am 1982;66:639-653.

Rabson AR, Koornhof HJ, Notman J, Maxwell WG. Hepatosplenic abscesses due to Yersinia enterocolitica. BMJ 1972;4:341.

Bouza E, Dominguez A, Meseguer M, Buzon L, Boixeda D, Revillo MJ et al. Yersinia enterocolitica septicaemia. Am J Clin Pathol 1980;74:404-409.

Robins-Browne RM, Rabson AR, Koornhof HJ. Generalized infection with Yersinia enterocolitica and the role of iron. Contrib Microbiol Immunol 1979;5:277-282.

Rabson AR, Hallet AF, Koornhof HJ. Generalized Yersinia enterocolitica infection. J Infect Dis 1975;131:447.

Brock JH. Iron and the outcome of infection. BMJ 1986;293:518-519.

Melby K, Slørdahl, Gutteberg TJ, Nordbø SA. Septicemia due to Yersinia enterocolitica after oral overdose of iron. BMJ 1982;285:467-468.

Robins-Browne RM, Prpic JK. Desferrioxamine and systemic yersinosis. Lancet 1983;10:1372-1372.

Abdelli N, Thiefin G, Chevalier P, Zeitoun P. Absces hepatiques a yersinia enterocolitica spontanement regressifs revelant une hemochromatose genetique: deuxieme cas. Gastroenterol Clin Bio 1996:20:212-213.

Jensen KT, Arpi M, Frederiksen W. yersinia enterocolitica septicaemia in Denmark 1972-1991: a report of 100 cases. Contrib Microbiol Immunol 1995;13:11

Additional Files

Published

2010-09-30

How to Cite

1.
Ferreira Gouveia P, Costa Dias V, Castro Gomes G. Yersinia enterocolitica bacteraemia and hemochromatosis – Case report. RPMI [Internet]. 2010 Sep. 30 [cited 2024 Dec. 18];17(3):159-60. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1212

Issue

Section

Case Reports

Most read articles by the same author(s)