Sweet’s syndrome– a case report

Authors

  • Pedro Figueiredo Serviço de Medicina 2 do Hospital Fernando da Fonseca E.P.E
  • Alda Garcia Serviço de Medicina 2 do Hospital Fernando da Fonseca E.P.E
  • Alice Rodrigues Serviço de Medicina 2 do Hospital Fernando da Fonseca E.P.E
  • Maria do Carmo Perloito Serviço de Medicina 2 do Hospital Fernando da Fonseca E.P.E
  • Luís Dutschmann Serviço de Medicina 2 do Hospital Fernando da Fonseca E.P.E

Keywords:

neutrophilic dermatosis, Sweet’s syndrome, ankylosing spondylitis, Crohn’s disease

Abstract

Although rare, the association of Sweet’s syndrome and Crohn’s
disease is established and considered an extra-intestinal manifestation of the disease.
The authors describe a case of this neutrophilic dermatosis on
a 65-year-old male with a background of ankylosing spondylitis
and Crohn’s disease, under immunosuppressive therapy, who
suddenly developed fever, arthralgias and widespread reddishpurple papular rash. Laboratory data revealed high inflammatory
markers. No infectious cause was found. The biopsy of two skin
lesions showed subepidermal edema and perivascular neutrophilic
infiltrate with no signs of vasculitis. Both the symptoms and the
rash gradually subsided about one week later, after initiation
of ibuprofen alongside the continuation of immunosuppressive
therapy. Clinical, laboratory and histological findings suggested
the diagnosis of Sweet’s syndrome and extracutaneous manifestations were not found

Downloads

Download data is not yet available.

References

Wallach D. Les dermatoses neutrophiliques. Rev Med Interne 2005; 26:41-53.

Vignon-Pennamen MD, Wallach D. The cutaneous manifestations of neutrophilic disease. Dermatologica 1991;183:255-264.

Leitão J et al. Síndrome de Sweet, afecção cutânea benigna ou sistémica grave? Revista Portuguesa de Medicina Interna 2006; 3 (1): 24-28.

Cohen PR, Kurzrock R. Sweet’s syndrome: a neutrophilic dermatosis classically associated with acute onset and fever. Clin Dermatol 2000;18:265-282.

Cohen Philip R. Sweet’s syndrome – a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis. 2007;2:34. doi: 10.1186/1750-1172-2-34.

Cohen Philip R et al. “Chapter 31. Acute febrile neutrophilic dermatosis (Sweet’s syndrome)” (Chapter). Wolff K et al: Fitzpatrick’s Dermatology in General Medicine, 7e: http://www.accessmedicine.com/content.aspx?aID=2952280

Von Den Driesch P. Sweet’s syndrome (acute febrile neutrophilic dermatosis). J Am Acad Dermatol 1994;31:535-556.

Timani S, Mutasim D. Skin manifestation of inflammatory bowel disease. Clin Dermatol 2008; 26: 265-273.

Veloso FT, Carvalho J, Magro F. Immune-related systemic manifestations of inflammatory bowel disease. A prospective study of 792 patients. J Clin Gastroenterol 1996; 23: 29-34.

Travis l et al. Sweet’s syndrome: an unusual cutaneous feature of Crohn’s disease or ulcerative colitis. The South West Gastroenterology Group. European journal of gastroenterology and hepatology. Eur J Gastroenterol Hepatology 1986; 9(7):715-720.

Vignon-Pennamen MD. The extracutaneous involvement in the neutrophilic dermatoses. Clin Dermatol 2000;18:339-347.

Cohen PR, Kurzrock R. Sweet’s Syndrome - A Review of Current Treatment Options. Am J Clin Dermatol 2002; 3 (2): 117-131

Additional Files

Published

2011-03-31

How to Cite

1.
Figueiredo P, Garcia A, Rodrigues A, Perloito M do C, Dutschmann L. Sweet’s syndrome– a case report. RPMI [Internet]. 2011 Mar. 31 [cited 2024 Sep. 7];18(1):26-30. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1299

Issue

Vol. 18 No. 1 (2011): Janeiro/ Março

Section

Case Reports

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2023 Medicina Interna

Open Access

Most read articles by the same author(s)

1 2 3 > >>