Dilated cardiomyopathy – new therapeutic approach
Keywords:
Dilated Cardiomyopathy, Immunoadsorption, Cardiac AutoantibodiesAbstract
Inflammatory reaction has been associated with dilated cardiomyo
pathy. In this context, cardiac autoantibodies and inflammatory cell
infiltration have been studied during the last two decades towards
the understanding of their origin and the underlying pathogenic
mechanisms. Recent research has increasingly focused on the
development of an etiological therapeutic approach.
Immunoadsorption has shown to improve clinical, echocardiographic, haemodynamic and laboratory parameters in patients
with inflammatory dilated cardiomyopathy.
In this article we review recent literature concerning this
subject, including classification, pathophysiological mechanisms and therapy.
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