Acute interstitial nephritis associated with omeprazol therapy

Authors

  • Marco Diogo Serviço de Medicina 2 do Hospital de São Marcos, Braga
  • Teresa Pimentel Serviço de Medicina 2 do Hospital de São Marcos, Braga
  • Manuela Rocha Serviço de Medicina 2 do Hospital de São Marcos, Braga
  • Isabel Tavares Serviço de Medicina 2 do Hospital de São Marcos, Braga

Keywords:

acute interstitial nephritis, acute renal insufficiency, omeprazol

Abstract

Acute renal insufficiency is a common problem found in our
internal medicine wards. In terms of differential diagnosis, acute
interstitial nephritis (AIN) is one of the possibilities that could be
easily forgotten especially in presence of several comorbidities
(namely neoplastic or infectious) and for that reason patients
taking several drugs which certainly difficults (and making it impossible ?) the identification of the responsible drug. The authors
report a case of AIN, confirmed by renal biopsy, in a patient with peptic ulcer taking omeprazol for 2 years.

Downloads

Download data is not yet available.

References

Kodner CM, Kudrimoti A. Diagnosis and management of acute interstitial nephritis. American Family Physician 2003; 67: 2527-2534.

Rossert J. Drug-induced acute interstitial nephritis. Kidney international 2001; 60 (2): 804-817.

Michel DM, Kelly CJ. Disease of the month: Acute interstitial nephritis. Journal of the American Society of Nephrology 1998;9:506-515.

Linton AL, Clark WF, Driedger AA et al. Acute interstitial nephritis due to drugs – review of the literature with a report of nine cases. Annals of internal medicine 1980; 93: 735-741.

Badov D, Perry G, Lambert J, Dowling J. Acute interstitial nephritis secondary to omeprazol. Nephrol Dial Transplant 1997; 12: 2414-2416.

Ruffenach SJ et al. Acute interstitial nefritis due to omeprazole. Am J Med 1992 ; 93 (4): 472-473.

Myers RP, McLaughlin KM, Hollomby DJ. Acute interstitial nephritis due to omeprazol. The American Journal of Gastroenterology 2001; 96: 3428-3431.

Wall CAM, Gaffney EF, Mellotte GJ. Hipercalcaemia and acute interstitial nephritis with omeprazol therapy. Nephrol Dial Transplant 2000; 15: 1450-1452.

Clarkson MR, Giblin L, O’Connell FP et al. Acute interstitial nephritis: clinical features and response to corticosteroid therapy. Nephrol Dial Transplant 2004; 19: 2778-2783.

Geevaninga N et al. Proton pump inhibitors and acute interstitial nephritis. Clin Gastroenterol Hepatol 2006; 4(5): 597-604.

Simpson IJ et al. Proton pump inhibitors and acute interstitial nephritis: report and analysis of 15 cases. Nephrology (Carlton) 2006; 11(5): 381-385

Additional Files

Published

2009-09-30

How to Cite

1.
Diogo M, Pimentel T, Rocha M, Tavares I. Acute interstitial nephritis associated with omeprazol therapy. RPMI [Internet]. 2009 Sep. 30 [cited 2024 Nov. 22];16(3):173-6. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1417

Issue

Section

Case Reports

Most read articles by the same author(s)