Addison’s Disease associated with pulmonary tuberculosis – a clinical case report
Keywords:
Addison´s disease, Primary Adrenal Insufficiency, Autoimmune Polyglandular Syndrome, Pulmonary TuberculosisAbstract
The authors present a case, of a 67 year-old male complaining
of intense asthenia, anorexia and weight loss, who had recently
developed nausea, vomiting, diarrhoea and prostration. Clinically
he was dehydrated and hypotensive and blood analyses revealed
serious hyponatraemia, hypochloraemia and hypo-osmolality, as
well as an increased erythrocyte sedimentation rate.
The reason for presenting this case is the diagnostic challenge
it poses and the need for emergency life-saving therapy.
A revision is made in the discussion, concerning Addison’s
disease in the context of the present case, as well as the unusual
simultaneous tuberculosis infection, which is discussed.
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References
Oelkers W. Current Concepts. “Adrenal Insufficiency”. N Engl J Med 1996;335: 1206-1212.
Odeke S, Nagelberg S. “Addison Disease”. eMedicine Journal 2001; 2: 5 (www.emedicine.com/med/topic42.htm).
Svetlana Tem, Maria New, Noel Maclaren. “Clinical Review-Addison’s Disease 2001”. J Clin Endocrinol Metab 2001; 86: 2909-2922.
Tierney L, McPhee S, Papadakis M. Current Medical Diagnosis and Treatment 39th Ed, Lange/ McGraw Hill 2000:1129.
Jameson J, Weetman A. Disorders of the Thyroid gland. In: Braunwald E, Fauci A, Kasper D et al eds. Harrison´s Principles of Internal Medicine 15th Ed. New York: McGraw-Hill. 2001:2060-2084.
Stefano Laureti, Patrick Aubourg et al. “Etiological Diagnosis of Primary Adrenal Insufficiency Using an Original Flowchart of Immune and Biochemical Markers”. J Clin Endocrinol Metab 1998; 9: 3163-3168.
Sunita C. Baxi. “Type II Autoimmune Polyglandular Syndrome: Case Report and Review of Literature”. The Endocrinologist 2001; 11:94-97.
Cook David M, Loriaux Lynn D. “The Incidental Adrenal Mass”. American Journal of Medicine 1996; 101:88-94.
O. González-Albarrán, R. Garcia Robles. “Insuficiencia Suprarrenal Primaria”. Medicine 2000; 8: 1141-1147.
Cohen N, Gilbert R, Wirth A et al. “Atrial natriuretic peptide and plasma renin levels in assessment of mineralocorticoid replacement in Addison´s disease”. J Clin Endocrinol Metab 1996; 81: 1411-1415.
Betterle C, Dal Pra C, Mantero F et al. “Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens and their applicability in diagnosis and disease prediction.”. Endoc Rev 2002; 23:327-364
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