Acute pancreatitis, criteria of severity and treatment orientation

Authors

  • Pedro Amaro Interno do Internato Complementar de Gastrenterologia, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Miguel Cabral Interno do Internato Complementar de Oncologia Médica, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Manuel Carlos Lemos Interno do Internato Complementar de Endocrinologia, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Joaquim Cardoso Interno do Internato Complementar de Medicina Interna, Hospitais da Universidade de Coimbra, Coimbra, Portugal
  • Maria José Nabais Assistente Hospitalar de Medicina Interna, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • José Pereira Moura Assistente Hospitalar de Medicina Interna, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • José Alves Moura Director do Serviço de Medicina II, Serviço de Medicina II dos Hospitais da Universidade de Coimbra

Keywords:

acute pancreatitis, infected pancreatic necrosis, hemosuccus pancreaticus

Abstract

The authors presenta case report of a 41-year-old male with severe alcoholic acute pancreatitis and extense infected pancreatic necrosis complicated by a hemosuccus pancreaticus. The criteria for the assessment of severity in acute pancreatitis, the diagnostic evaluation and therapeutic management in this condition are discussed.

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References

Ranson HJ, Rifkind KM, Rases DF, Fink SD, Eng K. Spencer FC. Prognostic sigos and the role of operative management in acute pancreatitis. Surg Gynaecol Obstei 1974; 139: 69-91.

Ranson HJC. The timing of biliary surgery in acute pancreatitis. Ann Surg 1979; 189: 654-662.

lmrie CW. Benjamin IS. McKay AJ. Mackenzie I. O'Neil J. Blumgart LH. A single centre double blind triai of Trasylol therapy in primary acute pancreatitis. Br J Surg 1978; 65: 337-341.

Blamey SL, lmrie CW, O'Neil J, Gilmour WM, Carter DC. Prognostic factors in acute pancreatitis. Gut 1984; 25: 1340-1346.

Corfield AP, Cooper MJ, Williamson RCN. et al. Prediction of severity in acute pancreatitis: a prospective comparison of three prognostic índices. Lancei 1985; II: 403-406.

Bradley EL III. A clinically based classification system for acute pancreatitis: Summary of the International Symposium on Acute Pancreatitis. Arch Surg 1993; 128: 586-590.

Formela LJ, Galloway SW, Kingsnorth AN. lnflammatory mediators in acute pancreatitis. Br J Surg 1995; 82: 6-13.

Norman JG, Fink GW, Franz MG. Acute pancreatitis induces intrapancreatic tumor necrosis factor gene expression. Arch Surg 1995; 130: 966-970.

McKay CJ, Gallagher G, Brooks B, Imrie CW, Baxter JN. Increased monocyte cytokine production in association with systemic complications in acute pancreatitis. Br J Surg 1996; 83: 919-923.

Kingsnorth NA, Galloway SW. Formela LJ. Randomised double blind phase II triai of lexipafant, a platelet activating factor antagonist, in human acute pancreatitis. Br J Surg 1995; 82: 1414- 1420.

McKay CJ, Currant F, Sharples C, Baxter JN, Imrie CW. Prospective placebo controlled randomised triai of lexipafant in predicted severe acute pancreatitis. Br J Surg 1997; 84: 1239- 1243.

Kingsnorth AN for lhe British Acute Pancreatitis Study Group. Early treatment with lexipafant, a platelet activating factor antagonist, reduces mortality in acute pancreatitis: a double blind, randomised placebo controlled study. Gastroenterology 1997; 112: A453.

Larvin M, McMahon MJ, APACHE II score for assessment and monitoring of acute pancreatitis. Lancei l 989;II:201-205.

Puolakkainen P, Valtonen V, Paananen A, Schroder T. C-reactive prateio (CRP) and serum phospolipase A2 in the assessment of the severity of acute pancreatitis. Gut 1987;28:764-771.

Funnell JC, Bornman PC, Weakley SP, Terblanche J, Marks IN. Obesity: an important prognostic factor in acute pancreatitis. Br J Surg 1993; 80: 484-486.

Gross V, Leser HG, Heinisch A, Scholmerich J. Inflammatory mediators and cytokines - new aspects of lhe pathophysiology and assessment of severity of acute pancreatitis? Hepato­ gastroenterology l 993;40:522-530.

lovanna JL, Keim V, Nordback I. et ai. Serum leveis of pancreatitis­ associated prateio as indicators of the course of acute pancreatitis. Multicentric Study Group on Acute Pancreatitis. Gastroenterology 1994; 106: 728-734.

Sainio V, Puolakainen P, Kemppainen EA. Serum trypsinogen-2 in lhe prediction of outcome in acute necrotizing pancreatitis. Scand J Gastroenterol 1996; 31: 818-824.

Malfertheiner P. Dominguez-Munoz JE. Prognostic factors in acute pancreatitis: Int J Pancreatol 1993; 14: 1-8.

Balthazar EJ, Robinson DL, Megibow AJ, Ranson JHC. Acute pancreatitis: value of CT in establishing prognosis. Radiology 1990; 174: 331-336.

Banks PA. Practice guidelines in acute pancreatitis. Am J Gastroenterol 1997; 92: 377-386.

Farkas G, Marton J, Mandi Y, Szederrenyi E. Surgical strategy and management of infected pancreatic necrosis. Br J Surg 1996; 83: 930-933.

Rau B, Uh! W, Buchler MW, Berger HG. Surgical treatment of infected necrosis. World J Surg 1997;21:155-161.

Rünzi M, Layer P, Niebel W, Eigler FW. Goebell H. Infected necrosis in severe acute pancreatitis: an indication for immediate surgery? Pancreas 1996; 13: A455.

Dubner H, Steinberg WH, Hill M, Bassi C. Chardavoyne R. Bank S. lnfected pancreatic necrosis and peripancreatic fluid collections: serendipitous response to antibiotic and medical therapy in three patients. Pancreas 1996; 12: 298-302.

Baron TH, Thaggard WG. Morgan DE. Stanley RJ. Endoscopic therapy for organized pancreatic necrosis. Gastroenetrology 1996; 111: 755-764.

Bradley EL Ili. Debugging pancreatic infections. Pancreas 1997; 14:205-206.

Additional Files

Published

1999-03-31

How to Cite

1.
Amaro P, Cabral M, Lemos MC, Cardoso J, Nabais MJ, Pereira Moura J, Alves Moura J. Acute pancreatitis, criteria of severity and treatment orientation. RPMI [Internet]. 1999 Mar. 31 [cited 2024 Dec. 18];6(1):43-9. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2036

Issue

Vol. 6 No. 1 (1999): Janeiro/ Março

Section

Case Reports

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