Antiphospholipid syndrome
Keywords:
antiphospholipid syndrome, anti-cardiolipin antibodies, deep venous thrombosisAbstract
The authors present the case of a 25 year-old patient, admitted to the Internai Medicine ward of the Centro Hospitalar de Coimbra,for fever syndrome. The clinicai picture and complementary investigations (echocardiography) allowed the diagnosis of Bacterial endocarditis to be made. The persistence of fever, after the disappearance of the endocardial vegetations, in association with a history of deep venous thrombosis and high titres for anti-cardiolipin antibodies (IgG> JOOU GPL); lead to the institution of corticosteroid therapy, with a successful resolution of the clinical picture, and allowed us to reach the final diagnosis - antiphospholipid syndrome.
Downloads
References
Asherson RA, e Moura JJ. Os anticorpos anticardiolipina nas doenças autoimunes. Acta Reumatológica Portuguesa 1987; XII (4): 227-
Brandt JT, Triplett DA, Alving B. Criteria for lhe diagnosis of lupus anticoagulants: an update. Thromb Haemost 1995; 74(4): 1185-
Boey ML, Colaço CB, Gharavi AE. Thrombosis in systemic lupus erytematosus: striking association with the presence of circulating lupus anticoagulants. British Medical Journal 1983; 287: 1021-1023
Branch W, Kochenour NK, Rote NS, Dostal DA Scott JR, Clinicai and laboratory features of the patients with lupus anticoagulant and recurrent pregnancy loss. Em "2nd World Symposium on Anti Phospholipid Antibodies" Londres 1986.
Harris EN. Diagnosis and management of antiphospholip syndrome. Hosp Pract 1994; 29(4): 65-76.
Harris EN, Chan JKH Asherson RA. Trombosis. recurrent fetal loss and thrombocytopenia: preditive value of lhe anticardiolipin antibody test. Arch lnt Med 1986; 146: 2153.
lnfant Rivard C, David M. Alving B el al. Lupus anticoagulants. anticardiolipin antibodies, and fetal loss: a case control study. N Eng J Med 1991; 325( 15): 1063-1066.
Khamashta MA, Cuadrado MJ, Mujic F et al. The managements of thrombosis in the antiphospholipid-antibody syindrome. N Eng! J Med 1995; 332(15). 993-997.
Additional Files
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2023 Medicina Interna
Open Access
