Autoimmune diseases of the nervous system

Authors

  • Manuel Gonçalves lnterno do lnternato Complementar de Neurologia, Serviço de Neurologia do Hospital de Santo António dos Capu­chos, Lisboa

Keywords:

autoantibody, autoimmune disea­ses, myasthenia gravis, inflammatory neuropa­thy, multiple sclerosis

Abstract

As a growing number of report suggests that neurologic diseases have a autoimmune basis, phisicians are confronted with new issues in diagnosis and treatment. At the sarne time, our understanding of antibody-induced neurologic disorders as been characterized in lhe last de­cade by an increasing knowledge of the molecu­lar specificities of autoantibodies. This review summarizes some current concepts in autoim­mune diseases of the nervous system.

Downloads

Download data is not yet available.

References

Drachman D. Myasthenia Gravis. ln J sselbacher, Braunwald, Wilson, Martin, Fauci, Kasper, eds, Harrison's Principies of Internai Medicine, 13th edition, pp 2393-2396, McGraw-Hill, Inc, 1994.

Oostherhuis H, Kuks J. Myasthenia Gravis and Myasthenic Syn­dromes. Curr Opin Neurol Neurosurg 1992; 5: 638-644.

Eymard B, Berrih AS. Rôle du Timus dans la Physiopathologie de la Myasthenie. Rev Neurol 1995; 151: 6-15.

Sreck A. Antibodies in the Neurology Clinic. Neurology 1990; 40: 1489-1492.

Kuks J, Limburg P, Horst G, et al. Antibodies to Skeletal Muscle in Myasthenia Gravis. Part 1. Diagnostic Value for the Detection of Timoma . J Neurol Sci 1993; 119: 183-188.

Kuks J, Limburg P, f-Jorst G, Oostherhuis H. Antibodies to Skele­tal Muscle in Myasthenia Gravis. Part 2. Prevalence in non­ Thymoma Patients. J Neurol Sci 1993; 120: 78-81.

Kuks J, Limburg P, Horst G, Oostherhuis H. Antibodies to Skele­tal Muscle in Myasthenia Gravis. Part 3. Relation With Clini­cal Course and Therapy. J Neurol Sci 1993; 120: 168-173.

Steck A: lnflammatory Neuropathy. Pathogenesis and Clinical Features. Curr Opin Neurol Neurosurg 1992; 5: 633-637.

Steck A, Kappos L. Gangliosides and Autoimmune Neuropathi­es. Classification and Clinical Aspects of Autoimmune Neuropathies. J Neur Neurosurg Psych 1994; (Suppl.) 57: 26-28.

llyas A, Mithen F, Chen Z, Cook S. Search for Antibodies to Neural Glycolipids in Séra of Patients with Guillain-Barré Syndrome. J Neuroç Sci 1991; 102: 67-75.

Fredman P, Vedeler C, Nyland H, et al. Antibodies in Sera from Patients with lnflammatory Demyelinating l'olyradiculoneu­ropathy React with Ganglioside LMl and Sulphatide of Pe­ripheral Nerve Myelin. J Neural 1991 ; 238 75-79.

Simone I, Annunziata P, Maimone D, et al. Serum and CSF anti-GMJ antibodies in Patients with Guillain-Barré Syndro­me and Chronic Inflammatory Demyelinating Polyneuro­pathy. J Neural Sei 1993; 114: 49-55

Steck A, Murray N, Dellagi K, et al. Peripheral Neuropathy Associated with Monoclonal lgM Autoantibody. Ann Neu­rol 1987; 22: 764-767.

Hauser S. Multiple Sclerosis and other Demyelinaring Disea­ses. ln Jsselbacher, Braunwald, Wilson, Maltin, Fauci, Kas­per, eds, Harrison's Principies of Internal Medicine, 13th edition, pp 2287-2295, McGraw-Hill, Jnc, 1994

Olsson T. Immunology of Multi pie Sclerosis. Curr Opin Neu­ral Neurosurg 1992; 5: 195-202.

Ransohoff R, Tuohy V, Lehmann P. The Immunology oi Multi­ pie Sclerosis: New lntricacies and New lnsights. Curr Opin Neural 1994; 7: 242-249

Hohlfeld R, Meinl E, Weber F, et al. The Role of Autoimmune T Lymphocytes in the Pathogenesis of Multiple Sclerosis. Neu rology 1995; 45 (suppl 6): S33-S38.

Warren K, Catz I, Johnson E, Mielke B. Anti-Myelin Basic Pro­tein and Anti-Proteolipid Protein Specific Fonns of Multi­ple Sclerosis. Ann Neurol 1994; :35: 280-289.

Faulds D, Benfield P. lnterferon beta-ib in Multiple Sclerosis. An lnitial Review of its Rational Use and Therapeutic Potential. Clin Immunother 1994; 1: 79-87.

Additional Files

Published

1997-06-30

How to Cite

1.
Gonçalves M. Autoimmune diseases of the nervous system. RPMI [Internet]. 1997 Jun. 30 [cited 2024 May 17];4(2):119-22. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2210

Issue

Section

Comunicações Breves

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)