Carcinoma de células de Merkel - A propósito de um caso clínico
Keywords:
skin cancer, Markel Cell Carcinoma, metastasis of unknown primary carcinomaAbstract
In the present work the authors make a presentantion of a clinical case relative to a woman of 80 years old, admitted in Internal Medicine Service grounds, by a question of lymph node metastasis of unknown primary carcinoma, that resulted in a diagnosis of 'Merkel Cell Carcinoma'. The case, taken on account its relative rarity, motivated a comprehensive review about the origin, pathoenesis, clinical behaviour and therapeutic solutions.
Downloads
References
Duncan WC et al. Spontaneous regression of Merkel cell ( neuro endocrine) carcinoma of the skin. J Am Acad Dermatol, 1993: 29: 653-654
Pardal de Oliveira F. et al. Primary Neuroendocrine ("Merkel-Cell") Carcinoma of the Skin - a clinico-pathological study of eleven cases. Arquivos de Medicina, 989;2: 249-254.
Ratner D, Nelson BR et ai. Merkel cell carcinoma. J Acad Dermatol. 1993; 29: 143-156
Rice RD et at. Merkel cell tumor of the head and neck: five new cases with literature review. Arch Otolaryngol Head Neck Surg. 1993: 119: 782-786.
Leonard JH. Leonard P. and Kearsley J.H. Chromosoms 1.11 and 13 are frequently involved in karyotypic abnormalities in metastatic Merkel cell carcinoma. Cancer Genet Cytogcnet. 1993: 67: 65-70.
Trimas ScottJ. et al. Pathologic diagnosis - Merkel cell carcinoma or primary neuroendocrine carcinoma of the skin. Arch Otolaryngol Head Neck Surg, 1992; 118: 998-1002.
Fenig E. Lurie H. et al. The treatment of advanced ,Merkel cell carcinoma. J Dermatol Surg Oncol. 1993; 19: 860-864.
Lynn GF et al. Chemotherapy for metastatic Merkel cell carcinoma. Cancer 62. 1988: 683-68S.
Jennifer AKP et al. Cancers of the skin. Cancer- principles and pratice of oncology, 3rd edition. 1989: 1469-1498.
Mackintosh J, Wills EJ Friedlander M.. Merkel cell tumours. Textbook of uncommon cancer. Whiley medical publication. chap
1988 913-923.
Tong AKF, Fitzpatrick TB, Neoplasms of the skin. Cancer Medi cine. third edition. Lea e Febiger, 1993: 1775-1792.
Wolf Gregrny T. et al. Head and Neck cancer. Cancer Medicine. third edition. Lea e Febier. 1993: 1211-127S.
Vire C. et al. Nonmelanoma skin cancer. J Am Acad Dermatol. 1988;133-137.
George FM, Martin CM. The skin. Robins - pathologic basis of disease. Saunders Company. 4th edition. 1989: 1277-1313.
Additional Files
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2023 Medicina Interna