Assistência a doentes com infecção pelo vírus da imunodeficiência humana: experiência num Serviço de Medicina Interna

Authors

  • Margarida Lucas Assistente Hospitalar de Medicina Interna do Hospital de Santa Maria
  • Ana E. Sousa Grau de Assistente Hospitalar de Medicina Interna do Hospital de Santa Maria
  • Vasco A. J. Maria Assistente da Faculdade de Medicina de Lisboa em Imu­nologia Clínica
  • Luísa Rebocho Interna da Especialidade de Medicina Interna do Hospi­tal de Santa Maria
  • M. João N. Silva Assistente Hospitalar de Medicina Interna do Hospital de Santa Maria
  • Rui M. M. Victorino Chefe de Serviço de Medicina Interna do Hospital de San­ta Maria; Professor Associado da Faculdade de Medicina de Lisboa Serviço de Medicina 2, Hospital Universitário de Santa Maria

Keywords:

AIDS, Internal Medicine, HIV1, HIV2, clinical manifestations, hospital care

Abstract

We report our experience on HIV infection in the context of an Internal Medicine Depart­ment in a Central Hospital, regarding both out­ patient and inpatient medical management. The clinical and epidemiological characteris­tics of the 54 patients (HIV1 - 46 and HIV2 - 8) as well as some diagnostic aspects of the opportunistic infections and of the antiviral therapy options are presented. We analyse the evolution of the patients throughout a medium follow-up period of two and halfyears as well as the significant impact in terms of hospital admissions. Emphasis is given to the motiva­tion and collaboration of all the health profes­sionals to face the difficult clinical problems of these patients in the context of an Internal Medicine Unit. Finally the role of the Internist in the health care of patients with HIV infecti­on is discussed and we argue in favour of a direct and continuous involvement of these specialists in all stages of the natural history of the disease.

Downloads

Download data is not yet available.

References

Volberding PA. Clinicai care of patients with AIDS - Developing a system. ln: Sande MA e Volberding P, ed. The Medical Ma­nagement of AIDS. Philadelphia: WB Saunders Company, 1992: 495-503.

Lucas M, Maria V, Sousa ME, Silva MJN, Victorino RMM. Experi­ência na área da infecção pelo HIV no contexto de um Servi­ço de Medicina Interna: avaliação de uma série clínica e de um questionário a pessoal de Saúde. Livro de Resumos do II Congresso Nacional de Medicina Interna 1992, pág. 36.

Mann JM, Carballo M. Social, cultural and political aspects: over­ view. AIDS (Current Science) 1989; 3: S221-S223.

De Moura MC, Serejo F, Ramalho F, VelosaJ, Palhano MJ, Baptista A. Diarreia e má-absorção associada a coccidiose intestinal (Isospora belli) num doente com a síndrome de imunodefi­ciência adquirida. Jornal do Médico 1985; CXIX (2149): 491-497.

Victorino R, Lucas M, Neto F and de Moura MC. HIV infection and intestinal pseudo-obstruction. AIDS (Current Science) 1990; 4: 599-601.

Sousa AE, Lucas M, Esperança P, Victorino RMM. Asymetric para­ paresis and hematologic autoimmune phenomena in HIV2 infection. Europ J Int Med 1993; 4: 333-335.

Victorino RMM e Maria VA. Espectro clínico das situações associ­adas à infecção pelo vírus HTLV-3/LAV. O Médico 1985; 113: 485-496.

Maria VAJ, Pinto LA, Victorino RMM. Inhibition of lymphocyte proliferation induced in vitro by microbial antigens in HIV­

-infected subjects.J Med Virol 1991; 35: 241-245.

Pinto L, Covas MJ, Victorino RMM. Loss of CD45RA and gain of CD45RO after in vitro activation of lymphocytes from HIV­ infected patients. Immunology 1991; 73: 147-150.

Pinto LA, Covas MJ, Victorino RMM. T-helper cross reactivity to viral recombinant proteins in HIV-2 infected patients. AIDS 1993; 7-10: 1389-1391.

Maria VAJ, Carvalho ML, Pimpão MV. Avaliação de atitudes e conhecimentos de clínicos gerais sobre infecção pelo vírus da imunodeficiência humana. Rev. Port. Clin. Geral 1994 (em publicação).

Maria VAJ, Lucas M, Sousa AE, Victorino RMM. Survey of attitu­des, knowledge and skills of physicians regarding HIV and AIDS in a large hospital in Lisbon. Proceedings of the IXth International Conference on AIDS, Berlim, 1993.

Victorino RMM, Maria VAJ, Jeffries DJ, Pinching A. Absence of HTLV-III/LAV antibodies in ex-residents from Angola and Mozambique returning to Portugal before 1979. Acta Médica Portuguesa 1986; 7: 49-50.

Victorino RMM, Guerreiro D, Lourenço MH, Ferreira MOS, Te­les LC. Prevalence of HIV-2 infection in a family planning clinic in Lisbon. Intern J Am and AIDS 1992; 3: 281-284.

Teles LC, Guerreiro D, Lourenço MH, Ferreira MOS, Victorino RMM. Análise da seroprevalência da infecção pelo HIV1 e HIV2 em mulheres residentes numa área da cidade de Lis­ boa. Acta Médica Portuguesa 1991; 4: 64-70.

Monteiro JA, Guimarães R, Sousa JA, Afonso L, Costa J., Morgado A e Proença R. Três anos de SIDA. Experiência do Hospital Curry Cabral com as infecções pelo HIV (1985-1988). Acta Médica Portuguesa 1989;6:270-275.

Cooper DA, Gatell JM, Kroon S, et al. Zidovudine in persons with asymptomatic HIV infection and CD4+ cell counts grea­ter than 400 per cubic millimeter. N Engl J Med 1993; 329: 297-303.

Volberding PA, Lagakos SW, Koch MA et al. Zidovudine in asymp­tomatic human immunodeficiency virus infection: a control­led trial in persons with fewer than 500 CD4-positive cells per cubic millimeter. N Engl J Med 1990; 32: 941-949.

Hamilton JD, Hartigan PM, Simberkoff MS, et al. A controlled triai of early/late treatment with Zidovudine symptomatic human immunodeficiency virus infection. N Engl J Med 1992; 326: 437-443.

Friedland GH. Early treatment for HIV: the time has come. N Engl J Med 1990; 322: 1000-1002.

Aboulker J-P, Swart AM. Preliminary analysis of the Concorde trial. Lancet 1993; 341: 889-890.

Additional Files

Published

1994-06-30

How to Cite

1.
Lucas M, E. Sousa A, Maria VAJ, Rebocho L, N. Silva MJ, Victorino RMM. Assistência a doentes com infecção pelo vírus da imunodeficiência humana: experiência num Serviço de Medicina Interna. RPMI [Internet]. 1994 Jun. 30 [cited 2024 Nov. 21];1(2):80-9. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2446

Issue

Section

Original Articles

Most read articles by the same author(s)