Complications and Relapse in a Mantle Cell Lymphoma Patient: A Case Report
DOI:
https://doi.org/10.24950/rspmi.2488Keywords:
Lymphoma, Mantle-Cell, Lung Diseases, Fungal, Organizing Pneumonia, SARS-CoV-2Abstract
Mantle cell lymphoma, a subtype of B-cell non-Hodgkin
lymphoma, is an incurable disease with an aggressive clinical course. In non-transplant eligible patients, chemotherapy regimens extend the overall and progression-free survival, at the expense of an increased risk of infectious complications.
The authors describe the case of a 73-year-old man, previously diagnosed with mantle cell lymphoma, under rituximab maintenance therapy, who presents with a series of infectious and non-infectious pulmonary complications. A radiological pattern of diffuse pulmonary infiltrates and a solitary nodule were the manifestations of multiple conditions, and, ultimately, the evidence for mantle cell lymphoma progression.
In this case, we recall that any new lung lesion in a known or treated case of lymphoma should be carefully evaluated for disease progression or recurrence. We also expose the intricate management of an immunocompromised patient with successive severe infections.
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