Therapeutic and Prophylactic Indications for Use of Proton Pump Inhibitors and Inappropriate Prescribing
DOI:
https://doi.org/10.24950/rspmi.2022.01.192Keywords:
Inappropriate Prescribing, Proton Pump Inhibitors/therapeutic useAbstract
Introduction: Proton pump inhibitors represent one of the most prescribed drug classes, often maintained without reevaluation of the need for treatment. The goals for this study were to identify the therapeutic and prophylactic indications of use, analyze the demographic characteristics of patients and the relative frequency of inappropriate use.
Material and Methods: Retrospective, observational, cross-sectional study, which consulted the clinical files of patients admitted in Internal Medicine Services of a District Hospital from June to October 2020, and whose usual medication included a proton pump inhibitor.
Results: 76.4% of patients (n = 233) were under proton pump inhibitors with no indication.
Conclusion: The fact that they are not subjected to a prescription, contributed to their excessive and growing consumption without medical opinion. However, it is essential to evaluate the indications for treatment and inappropriate use as several studies have exposed potential adverse reactions associated with prolonged exposure.
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