From Social Issue To Neurosurgery: A Case Of Panhypopituitarism

Authors

  • Ana Margarida Fernandes Serviço de Medicina Interna, Centro Hospitalar de Vila Nova Gaia/Espinho, Portugal
  • Pedro Mesquita Oliveira Serviço de Medicina Interna, Centro Hospitalar de Vila Nova Gaia/Espinho, Portugal
  • Gustavo Rocha Serviço de Endocrinologia, Centro Hospitalar de Vila Nova Gaia/Espinho, Portugal
  • Manuela Sequeira Serviço de Medicina Interna, Centro Hospitalar de Vila Nova Gaia/Espinho, Portugal
  • Fernando Rosas Vieira Serviço de Medicina Interna, Centro Hospitalar de Vila Nova Gaia/Espinho, Portugal

DOI:

https://doi.org/10.24950/rspmi.806

Keywords:

Diabetes Insipidus, Hypernatremia, Hypopituitarism, Polyuria

Abstract

Panhypopituitarism results from a low or absent pituitary function
and its recognition is challenging. We report the case of
a 42-year old female, mentally handicapped overweight, short
stature that was brought to the emergency room for gonarthrosis.
After medical discharge, she was admitted as a social case.
It was then noticed that she displayed polydipsia, polyuria and
primary amenorrhea. Complementary exams showed panhypopituitarism
and cerebral magnetic resonance imaging study
showed an arachnoid cyst of congenital nature. She was submitted
to surgical and medical care with positive evolution. An
early approach could have dramatically altered the life-course
of this patient. Her low economic status allowed for this clinical
picture to go unnoticed, however it was also the event that led
to the current clinical investigation. We wish to emphasize the
clinical polymorphism of panhypopituitarism and the need for a
high index of suspicion, even in difficult social contexts.

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References

Larson A, Nokoff NJ, Meeks NJ. Genetic causes of pituitary hormone deficiencies. Discov Med. 2015; 19: 175-83.

Rose BD, Post TW. Clinical physiology of acid-base and electrolyte disorders. 5th ed. New York: McGraw-Hill; 2001.

Carmody D, Hannon MJ, Thompson C. Vasopressin, diabetes insipidus and the syndrome of inapropriate antidiuretic hormone secretion. In:

Jameson JL, De Groot LJ, editors. Endocrinology: Adult and Pediatric. 6th ed. Vol. 21. Philadelphia: Saunders Elsevier; 2010. p. 386-99.

Hannon MJ, Thompson C. Hyponatremia and Hypernatremia. In: Jameson JL, De Groot LJ, editors. Endocrinology: Adult and Pediatric.

th ed. Vol. 21. Philadelphia: Saunders Elsevier; 2010. p. 2053-62.

Robinson AG, Verbalis JG. Posterior pituitary. In: Kronenderg HM, Melmed S, Polonsky KS, Larsen PR, editors. Williams Textbook of Endocrinology. 11th ed. Vol.9. Philadelphia: Saunders Elsevier; 2008. p. 263-95.

Oiso Y, Robertson GL, Norgaard JP, Juul KV. Clinical review: Treatment of neurohypophyseal diabetes insipidus. J Clin Endocrinol Metab. 2013; 98:3958.

De Boer H, Blok GJ, Van Der Veen EA. Clinical aspects of growth hormone deficiency in adults. Endocr Rev. 1995; 16:63.

Practice Committee of the American Society for Reprodutive Medicine. Current evaluation of amenorrhea. Fertil Steril. 2008: ; 90(5

Suppl):S219-25.

Additional Files

Published

2016-06-30

How to Cite

1.
Fernandes AM, Mesquita Oliveira P, Rocha G, Sequeira M, Rosas Vieira F. From Social Issue To Neurosurgery: A Case Of Panhypopituitarism. RPMI [Internet]. 2016 Jun. 30 [cited 2024 Dec. 4];23(2):102-4. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/806

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Section

Case Reports

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