Follicular Dendritic Cell Sarcoma in Mesentery Lymph Node: A Case Report
DOI:
https://doi.org/10.24950/rspmi.842Keywords:
Lymph Nodes, Immunohistochemistry, Follicular Dendritic Cells SarcomaAbstract
Follicular dendritic cell sarcoma is an extremely rare neoplasm,
with only few published cases. Remaining under-recognized,
misdiagnosis is common. Considered of intermediate malignant
potential, it can involve lymph nodes or extranodal sites.
This tumor is a diagnostic challenge that requires confirmation
through immunohistochemical methods. The treatment is not
well established due to limited clinical experience, but is based
on surgical excision. We describe a case of a 50-year-old-woman,
previously healthy, with gradual complaints of weight loss,
anorexia, asthenia, left abdominal pain and fever. The complementary
study was inconclusive, until computed tomographic
scan showed a nodular lesion on the left flank at the level of the
mesentery. She was submitted to an aspiration biopsy with unsatisfactory
results so the patient underwent successful surgical
excision of the tumor. Histopathological examination revealed
neoplasm composed of spindled cells, with marked pleomorphism
and numerous mitotic figures and immunohistochemical
study allowed the final diagnosis.
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