Histiocitose pulmonar de células de Langerhans – a propósito de um caso clínico
Palavras-chave:
pneumotórax, histiocitose pulmonar, células de LangerhansResumo
A histiocitose pulmonar de células de Langerhans é uma doença rara, de etiologia
desconhecida, associada ao consumo tabágico, caracterizada por uma anormal
proliferação de células de Langerhans, com formação de lesões nodulares e de evolução
variável. Os A.A. apresentam o caso clínico de um jovem de 15 anos, internado no
serviço de Pneumologia do Hospital São João, por pneumotórax bilateral. No estudo
clínico efectuado observou-se, na TAC torácica de alta resolução, lesões
predominantemente císticas, 12% de células CD1a+ no LBA e, na biopsia
transbrônquica, nódulos com elevado número de células do tipo histiocitário, com
imunorreactividade positiva para CD1a e S100, obtendo-se o diagnóstico de histiocitose
de células de Langerhans. De seguida e a propósito do caso clínico apresentado,
procede-se a uma análise desta patologia, nomeadamente no que concerne às
características clínicas, radiológicas e patológicas, além do seu diagnóstico e
tratamento.
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