Pulmonary Langerhans’ cell histiocytosis- a clinical case report
Keywords:
pulmonary histiocytosis, Langerhans’ cells, pneumothoraxAbstract
Pulmonary Langerhans’ Cell Histiocytosis is a rare disease of unknown aetiology. It’s a
smoking related disease and it’s characterized by an abnormal Langerhans’ cell
proliferation forming nodular lesions. It has a variable and unpredictable course. The
authors present a clinical case of a 15 years old male who presented a bilateral
pneumothorax. The Pulmonary Langerhans’ Cell Histiocytosis diagnosis was based on a
HRCT scan predominantly with cystic lesions, BAL with 12% CD1a+ cells and the
presence of nodules with a high number of histiocytic cells, positive to CD1a and S100
in the transbronchial biopsy. The authors also made a review about this pathology,
namelly it’s clinical, radiological, histological, diagnosis and therapeutic features.
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