Síndrome de DRESS: Uma Revisão Baseada num Caso Clínico

Authors

DOI:

https://doi.org/10.24950/rspmi.2353

Keywords:

Exantema, Período Pós-Parto, Síndrome de Hipersensibilidade a Medicamentos

Abstract

A síndrome DRESS é uma doença rara, mas potencialmente fatal, que pode cursar com erupções cutâneas e envolvimento multiorgânico.

Relatamos o caso de uma puérpera de 28 anos que desenvolveu exantema cutâneo 2 meses após o parto por cesariana, com dores musculares, odinofagia, tosse e febre. A erupção cutânea começou nos membros inferiores e progrediu
por todo o corpo. Foi medicada com ceftriaxone durante o parto, tendo também histórico de uso de diclofenac e metildopa. Pontuou 6 no score RegiSCAR, confirmando o diagnóstico de síndrome DRESS. A paciente também desenvolveu hepatite tóxica, motivando tratamento com corticoterapia
intravenosa. Após 2 semanas de tratamento e evicção dos fármacos responsáveis, teve alta com melhora clínica e laboratorial.

Este caso destaca a importância do diagnóstico e tratamento imediatos das reações farmacológicas tardias, especialmente da síndrome DRESS, cujo diagnóstico pode ser desafiador devido à sua apresentação tardia.

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Published

2025-03-31

How to Cite

1.
Fernandes Moura P, Albuquerque Monteiro I, Lima Silva A, Correia Cardoso J, Macedo Neves P. Síndrome de DRESS: Uma Revisão Baseada num Caso Clínico. RPMI [Internet]. 2025 Mar. 31 [cited 2025 Apr. 1];32(1):28-33. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2353

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