DRESS Syndrome: A Review Based on a Clinical Report

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DOI:

https://doi.org/10.24950/rspmi.2353

Palavras-chave:

Drug Hypersensitivity Syndrome, Exanthema, Postpartum Period

Resumo

DRESS syndrome is a rare but potentially life-threatening disease that may present with multiorgan involvement and cutaneous eruptions.

We report the case of a 28-year-old puerperal woman who developed a cutaneous exanthema 2 months after cesarean delivery, along with muscle pain, odynophagia, cough, and fever. The cutaneous eruption started on the lower limbs and
progressed throughout the entire body. The patient had received ceftriaxone intravenously during delivery and had a history of oral intake of diclofenac and methyldopa. Scored 6 on RegiSCAR,
confirming the diagnosis of DRESS syndrome. The
patient also developed toxic hepatitis, which was managed with intravenous corticotherapy. After 2 weeks of treatment and the removal of probable drugs, the patient was discharged with clinical and laboratory improvement.

This case highlights the importance of prompt diagnosis
and treatment of late pharmacological reactions, particularly
DRESS Syndrome, which can be challenging to diagnose due
to its delayed presentation.

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Publicado

31-03-2025

Como Citar

1.
Fernandes Moura P, Albuquerque Monteiro I, Lima Silva A, Correia Cardoso J, Macedo Neves P. DRESS Syndrome: A Review Based on a Clinical Report. RPMI [Internet]. 31 de Março de 2025 [citado 2 de Abril de 2025];32(1):28-33. Disponível em: https://revista.spmi.pt/index.php/rpmi/article/view/2353

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