Toxic shock syndrome: an underdiagnosed illness – a case report
Keywords:
Toxic shock syndrome, Systemic inflammatory response, Multiple organ failureAbstract
Staphylococcal toxic shock syndrome is a rare and potentially fatal
illness. Frequently the diagnosis is missed as the initial clinical
features are non-specific. The progression to a toxic condition,
caused by the systemic inflammatory response to toxins produced
by bacteria, is rapid and unless definitive treatment measures are
initiated in the early hours, the end result can be catastrophic due
to multiple organ failure. We report a previously healthy patient
who had features of toxic shock syndrome due to infection by
Staphylococcus aureus, with multiple organ involvement, being
treated successfully with antibiotics and aggressive care support.
This case shows the high morbidity associated to this syndrome;
however successful outcome is possible provided the patient is
kept under close monitoring and proper early treatment is started.
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References
Todd J. Toxic shock syndrome. Clin Microbiol Rev 1988; 1: 432-446.
Todd J, Fishaut M, Kapral F, Welch T. Toxic shock syndrome associated with phage-group-I staphylococci. Lancet 1978; ii: 1116-1118.
Davis JP, Chesney PJ, Wand PJ, Laventure M. Toxic-shock syndrome: epidemiologic features, recurrence, risk factors, and prevention. N Engl J Med 1980; 303: 1429-1435.
Shands KN, Schmid GP, Dan BB et al. Toxic shock syndrome in menstruating women: association with tampon use and Staphylococcus aureus and clinical features in 52 cases. N Engl J Med 1980; 303: 1436-1442.
Reingold AL, Dan BB, Shands KN, Broome CV. Toxic-shock syndrome not associated with menstruation. A review of 54 cases. Lancet 1982; i: 1-4.
Reingold AL, Hargrett NT, Dan BB, Shands KN, Strickland BY, Broome CV. Nonmenstrual toxic shock syndrome: a review of 130 cases. Ann Intern Med 1982; 96: 871-874.
Morrison VA, Oldfield EC. Postoperative toxic shock syndrome. Arch Surg. 1983; 118: 791-794.
Fischer M, Bhatnagar J, Guarner J, Reagan S, Hacker JK. Fatal Toxic Shock Syndrome Associated with Clostridium sordellii after Medical Abortion. N Engl J Med; 2005. 353:2352-2360.
Habif TP. Exanthems and Drug Eruptions. In: Habif TP, ed. Clinical Dermatology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2009: chapter 14: 544-580.
Chesney PJ, Davis JP, Purdy WK, Wand PJ, Chesney R W. Clinical manifestations of toxic shock syndrome. J. Am. Med. Assoc. 1981. 246:741-748.
Wiesenthal A M, Ressman M, Caston S A, Todd J K. Toxic shock Syndrome. I. Clinical exclusion of other syndromes by strict and screening definitions. Am. J. Epidemiol. 1985. 122:847-856.
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