Primary effusion lymphoma in a HIV infected patient
Keywords:
HIV infection, fever of unknown origin, pleural effusion lymphomaAbstract
The primary lymphoma of cavities is a rare subtype of non-Hodgkin
(NHL) with reserved prognosis, characterized by the proliferation
of malignant cells exclusively in serosal cavities and is associated
with infection by type 8 human herpes virus. It is more often described in immunosuppressed patients, particularly in the context
of Acquired Immunodeficiency Syndrome (AIDS).
We present a case of a patient diagnosed with AIDS, admitted
in hospital for fever and systemic complaints. During the hospitalization he developed insidiously ascites, right pleural effusion
and pericardial effusion. The ascitic fluid presented large lymphoid cells with non-B non-T phenotype. The study performed
did not detect solid tumors, lymphadenopathies or bone marrow
involvement. It was not possible to demonstrate lymphoid cells
infection by HHV-8; clinical, cytologic and immunophenotypic data
strongly suggest the diagnosis of primary lymphoma of cavities.
The patient died 41 days after the diagnosis, before chemotherapy
had been attempted.
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