Coexistence of two causes of hipercoagulability – case report

Authors

  • Filipa Malheiro Interna do Internato Complementar de Medicina Interna, Serviço de Medicina 1 do Hospital Egas Moniz, Lisboa
  • Rita Mendes Interna do Internato Complementar de Medicina Interna, Serviço de Medicina 1 do Hospital Egas Moniz, Lisboa
  • Eugénia Santos Assistente Hospitalar de Medicina Interna, Serviço de Medicina 1 do Hospital Egas Moniz, Lisboa
  • Isabel Gaspar Assistente Hospitalar Graduada de Medicina Interna, Serviço de Medicina 1 do Hospital Egas Moniz, Lisboa
  • Isabel Madruga Assistente Hospitalar Graduada de Medicina Interna, Serviço de Medicina 1 do Hospital Egas Moniz, Lisboa
  • Pedro Abecassis Director do Serviço de Medicina I Serviço de Medicina 1 do Hospital Egas Moniz, Lisboa

Keywords:

thrombophilia, deep vein thrombosis, antiphospholipid syndrome, prothrombin G20210A mutation

Abstract

The authors describe the clinical case of a 38-year-old woman
with history of high blood pressure during pregnancy, two episodes of deep vein thrombosis in different territories of the lower
limbs, hand arthralgia, migraine and Raynaud’s phenomenon. The
aetiological investigation revealed positive antinuclear antibodies
with homogeneous pattern (1/320), positive anti-DNA antibodies,
transitory protein S deficiency, positive anticardiolipin antibodies
(moderate and high levels of IgG on two occasions), positive
anti- 2-glycoprotein I antibodies and genetic study compatible
with heterozygosity for the prothrombin G20210A mutation. The
authors discuss the antiphospholipid syndrome and the primary
versus secondary antiphospholipid syndrome criteria, the coexistence of other coagulation disorders and their treatment.

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References

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Additional Files

Published

2004-06-30

How to Cite

1.
Malheiro F, Mendes R, Santos E, Gaspar I, Madruga I, Abecassis P. Coexistence of two causes of hipercoagulability – case report. RPMI [Internet]. 2004 Jun. 30 [cited 2024 May 17];12(2):73-6. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1681

Issue

Vol. 12 No. 2 (2005): Abril/ Junho

Section

Case Reports

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