Alcohol Withdrawal Syndrome - a retrospective study

Authors

  • Paulo P. Marques Interno de Gastrenterologia, Departamento de Medicina Interna, Serviço de Gastrenterologia do Hospital Garcia de Orta, Lisboa
  • João Namora Assistente Graduado de Medicina Interna, Departamento de Medicina Interna, Serviço de Gastrenterologia do Hospital Garcia de Orta, Lisboa
  • Álvaro de Carvalho Director do Serviço de Medicina Interna Departamento de Medicina Interna, Serviço de Gastrenterologia do Hospital Garcia de Orta, Lisboa

Keywords:

alcohol withdrawal syndrome, alcohol, retrospective study

Abstract

Alcohol consumption in our country remains high,
with effects in different health areas, namely at the in-patient level. In this article we aimed to study the
natural history of alcohol withdrawal syndrome, the different therapeutic approaches and the reference
strategies after discharge. In order to do so, a
retrospective study was performed and 81 in-patients
with the diagnosis (primary or secondary) of alcohol
withdrawal syndrome were studied. The most frequent
complications encountered were rhabdomyolysis (51%)
and seizures (39%). The drugs most often used
therapeutically were neuroleptics and benzodiazepines.
After discharge, there was no patient referral or follow-up in half of the cases. We concluded that alcohol
withdrawal syndrome is a frequent diagnosis and there
is a need for the implementation of therapeutic
protocols and better follow-up after discharge, if we
want to change the natural history of this disease. 

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References

O’Connor P, Schottenfeld R. Patient with alcohol problems. NEJM 1998;338 (9): 592-601.

Schuckit M. Alcohol and Alcoholism. In: Fauci AS, Braunwald E, Isselbacher KJ et al. editors. Harrison’s Principles of Internal Medicine. 14 th edition: McGraw Hill 1998: 2503-2508.

Hall W, Zador D. The alcohol withrawal syndrome. Lancet 1997; 349: 1897-1900.

Saitz R, O’Malley SS. Pharmacotherapies for alcohol abuse. Medical Clinics of North America 1997; 81(4): 881-901.

Erstad B, Cotugno C. Management of alcohol withdrawal. Am j health syst pharm 1995; 52: 697-709.

Evans DJ, Street SD, Lynch DJ. Alcohol withrawal at home. Canadian Family Physician 1996; 42: 937-945.

Gabutti I, Mombelli G. Abus d’alcool et de drogues: une analyse rétrospective de l’incidence dans un hõpital régional 1993-1994. Schweiz Med Wochenschr 1996; 126: 2130-2135.

Foy A, Kay J, Taylor A. The course of alcohol withrawal in a general hospital. Q J Med 1997; 90: 253-261.

Etherington JM. Emergency management of acute alcohol problems. Canadian Family Phycician 1996; 42: 2186-2190.

Mattick RP, Hall W. Are detoxification programmes effective?. Lancet 1996; 347(8994): 97-100.

Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM. Assessment of alcohol withrawal: the revised clinical institute withrawal

assessment for alcohol scale (CIWA-Ar). Br J Addict 1989; 84: 1353-1357.

Mayo-Smith MF. Pharmacological management of alcohol withdrawal: a meta analysis and evidence-based practice guideline: American society of addiction medicine working group on Pharmacological Management of alcohol withdrawal. JAMA 1997; 278(2): 144-151.

Dubuc L, Defer G. Alcoolisme: Syndrome de severage. La Revue du Praticien 1996; 46: 2021-2024.

Lohr RH. Treatment of alcohol withrawal in hospitalized patients. Mayo clin proc 1995; 70: 777-782.

Cook C, Thomson AD. B complex vitamins in the prophylaxis and treatment of wernicke-korsakoff syndrome. British journal of hospital

medicine 1997; 57(9): 461-465.

Peppers MP. Benzidiazepines for alcohol withrawal in the eldery and in patients with liver disease. Pharmacotherapy 1996; 16 (1): 49-58.

Bates D.Pharmacotherapy debate on alcohol withrawal syndrome (Letter). Canadiam Family Physician 1997; 43: 1209-1212.

Peters DH, Faulds D. Tiapride. A review of its pharmacology and therapeutic potencial in the management of alcohol dependence syndrome. Drugs 1994; 47(6): 1010-1032.

Mezciems PE. Withrawal strategies for outpatients. Canadian Family Physician 1996; 42: 1745-1752.

Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG. Goodman & Gilman’s The pharmacological basis of therapeutics. 9 th

edition. McGraw Hill 1996: 421-424.

Haack MR. Treating acute withrawal from alcohol and other drugs. Nursing Clinics of North America 1998; 33(1): 75-92

Additional Files

Published

2001-09-28

How to Cite

1.
Marques PP, Namora J, de Carvalho Álvaro. Alcohol Withdrawal Syndrome - a retrospective study. RPMI [Internet]. 2001 Sep. 28 [cited 2024 May 18];8(3):159-64. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1913

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