Auto-Inflammatory Diseases - a new pathophysiological concept
Keywords:
Auto-inflammatory diseases, pirin, marenostrin, TNF receptor, TRAPSAbstract
The concept of auto-inflammatory disease based
on the ocurrence of non-organ specific inflammatory
episodes, absence of evident causative events,
absence of auto-antibodies and absence of antigen-specific lymphocytes. The physiopathologic role of
pirin/marenostrin in Familiar Mediterranean Fever
and of TNF receptor in TRAPS is presented.
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