Gilbert's syndrome - A short review

Authors

  • J. Vilela Gonçalves Interno do Internato Complementar de Medicina Interna, Serviço Universitário de Medicina Interna e de Gastrenterolo­gia do Hospital Pulido Valente, Lisboa
  • J. Leitão Assistente Hospitalar de Gastrenterologia, Serviço Universitário de Medicina Interna e de Gastrenterologia do Hospital Pulido Valente, Lisboa
  • B. Rodrigues Assistente Hospitalar de Gastrenterologia, Serviço Universitário de Medicina Interna e de Gastrenterologia do Hospital Pulido Valente, Lisboa
  • A. M. Mouro Chefe de Serviço de Medicina Interna, Serviço Universitário de Medicina Interna e de Gastrenterolo­gia do Hospital Pulido Valente, Lisboa
  • M. G. Quina Director de Serviço, Serviço Universitário de Medicina Interna e de Gastrenterolo­gia do Hospital Pulido Valente, Lisboa

Keywords:

jaundice, bilirubin metabolism, ca­loric restriction

Abstract

Gilbert's syndrome is the most common ano­maly of bilirubin transportation. The controver­sy of its existence has centred on the nature of the distribution of serum bilirubin concentrati­ons in healthy people. The authors advert to the necessity to reassure the patient with regard to the benign and inconsequential nature of the di­sorder and the excellent prognosis.

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References

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Muraca M, Fevery J. Influence of sex and sex steroids on biliru­bin uridine diphosphate-glucoronyl transferase activity of rat liver. Gastrenterology 1984; 87: 308-313.

Black M, Billing BH. Hepatic bilirubin UDP glucoronyl transfe­rase activity in liver disease and Gilbert's Syndrome. NEJM 1969; 280: 1266-1271.

Editorial. Gilbert's Syndrome: more questions than answers. Lancet 1987; 1071.

Olson R, Bliding A, Jagenburg R, Lapidus L, Larson B, Svardsu­dd K, Wittbolcl S. Gilbert's Synclrome: does it exist ? Acta Med Scand1988; 224: 485-490

Gollan J, Bateman C, Billing BH. Effect of dietary composition on the unconjugated hyperbilirubinaemia of Gilbert's Syn­drome. Gut 1976; 17: 335-440.

Gollan J, Schmidt R. Bilirubin metabolism and hyperbilirubi­naemia disorders. ln: Wright R, Millward-Sadler GH, Al­berti KGMM, Karran S eds Liver and biliary disease 2nd Ed. Philadelphia Bailliere Tindall, WB Saunders: 1985: 301-357.

Shearman D. Jaundice and cholestasis. ln: Shearman D, Fin­ laysson N, eds. Diseases of the gastrointestinal tract and liver 2nd. Ed, Churchill Livingstone.

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Additional Files

Published

1997-03-31

How to Cite

1.
Gonçalves JV, Leitão J, Rodrigues B, Mouro AM, Quina MG. Gilbert’s syndrome - A short review. RPMI [Internet]. 1997 Mar. 31 [cited 2024 Nov. 24];4(1):53-5. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2192

Issue

Vol. 4 No. 1 (1997): Janeiro/ Março

Section

Review Articles

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