Non-Steroidal Mineralocorticoid Receptor Antagonists, a New Pharmacological Class - What's the Future?

Autores

DOI:

https://doi.org/10.24950/rspmi.2642

Palavras-chave:

Mineralocorticoid Receptor Antagonists/administration & dosage, Mineralocorticoid Receptor Antagonists/adverse effects

Downloads

Não há dados estatísticos.

Referências

Zannad F, McMurray JJ, Krum H, van Veldhuisen DJ, Swedberg K, Shi H, et al. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med. 2011;364:11-21. doi: 10.1056/NEJMoa1009492.

Bakris GL, Agarwal R, Anker SD, Pitt B, Ruilope LM, Rossing P, et al. Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes. N Engl J Med. 2020;383:2219-29. doi: 10.1056/NEJMoa2025845.

Pitt B, Filippatos G, Agarwal R, Anker SD, Bakris GL, Rossing P, et al. Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes. N Engl J Med. 2021;385(:2252-63. doi: 10.1056/NEJMoa2110956.

Agarwal R, Filippatos G, Pitt B, Anker SD, Rossing P, Joseph A, et al. Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis. Eur Heart J. 2022;43:474-84. doi: 10.1093/eurheartj/ehab777.

Solomon SD, McMurray JJ, Vaduganathan M, Claggett B, Jhund PS, Desai AS, et al. Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction. N Engl J Med. 2024;391:1475-85. doi: 10.1056/NEJMoa2407107.

Iwahana T, Saito Y, Okada S, Kato H, Ono R, Kobayashi Y. Safety and efficacy of esaxerenone in Japanese hypertensive patients with heart failure with reduced ejection fraction: A retrospective study. PLoS One. 2021;16:e0259485. doi: 10.1371/journal.pone.0259485.

Downloads

Publicado

31-07-2025

Como Citar

1.
Jeremias Macedo M, Augusto D, Borges Coelho T. Non-Steroidal Mineralocorticoid Receptor Antagonists, a New Pharmacological Class - What’s the Future?. RPMI [Internet]. 31 de Julho de 2025 [citado 2 de Agosto de 2025];32(2):127-8. Disponível em: https://revista.spmi.pt/index.php/rpmi/article/view/2642