Cardiomiopatia dilatada – nova abordagem terapêutica

Autores

  • Joana Estácio Pharmacology Department of the Medical Sciences School; New Lisbon University Medical Service 4, Santa Marta Hospital, Central Lisbon Hospital Center
  • José Cardoso Pharmacology Department of the Medical Sciences School; New Lisbon University Medical Service 4, Santa Marta Hospital, Central Lisbon Hospital Center

Palavras-chave:

Cardiomiopatia dilatada, imunoadsorção, auto-anticorpos cardíacos

Resumo

A cardiomiopatia dilatada ocorre na presença de uma reacção
inflamatória. Neste contexto, nas últimas duas décadas tem sido
estudada a existência de auto-anticorpos cardíacos assim como
o processo de infiltração cardíaca por células inflamatórias. Hoje
em dia percebem-se melhor os mecanismos patogénicos subjacentes ao processo. Recentemente, o esforço de investigação
nesta área centrou-se numa abordagem terapêutica em função da
etiologia. O processo de remoção de auto-anticorpos circulantes
pelo método da imunoadsorção tem demonstrado bons resultados
clínicos, ecocardiográficos, hemodinâmicos e laboratoriais na
cardiomiopatia dilatada. Neste artigo pretendeu-se rever o tema
abordando a literatura recente sobre classificação da doença,
mecanismos fisiopatológicos e terapêutica.

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Publicado

31-03-2011

Como Citar

1.
Estácio J, Cardoso J. Cardiomiopatia dilatada – nova abordagem terapêutica. RPMI [Internet]. 31 de Março de 2011 [citado 11 de Outubro de 2024];18(1):55-8. Disponível em: https://revista.spmi.pt/index.php/rpmi/article/view/1306

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