Síndroma de Sjögren Primária – revisão
Palavras-chave:
Sindroma de Sjögren, xerostomia, xeroftalmia, parotidite, nefrite, pneumonite, tiroide, arteriteResumo
A síndroma de Sjögren (S.S.) é uma doença inflamatória auto-imune, lentamente
progressiva que, predominantemente, afecta as glândulas exócrinas, clinicamente
dominada pelos sintomas sicca (xerostomia e xeroftalmia), mas que pode, apresentar
quadros clínicos diversos, com sintomas e sinais subtis, de desenvolvimento insidioso, e
por isso, muitas vezes de reconhecimento e diagnóstico difícil.
É considerada por alguns o “grande imitador”, pois pode mimetizar ou coexistir com
outras doenças auto-imunes específicas de órgão, doenças hematológicas ou neurológicas.
Atendendo a estas características, compreender-se-á que , sendo embora uma entidade
comum, seja tão subdiagnosticada e alguns lhe chamem a “doença órfã ”.
Os AA. fazem uma revisão teórica dos aspectos clínicos, histopatológicos,
imunológicos e terapêuticos desta doença.
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Referências
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