Behçet Disease – Clinical manifestations of 12 patients of an Autoimmune Disease Unit
Keywords:
Behçet disease, uveitis, oral ulceration, genital ulceration, rythema nodosum, vasculitisAbstract
The authors present a retrospective study of 12 patients with
Behçet’s disease. All patients fulfilled diagnostic criteria for BD
(International Study Group for BD, 1990).
All patients were Portuguese and Caucasians. There were 12
patients, 9 female and three male. Mean age at onset of BD was
31.3 years. All patients presented recurrent oral ulceration and
66.7% also had genital ulceration. Nine patients (75%) had ocular
involvement. Dermatological manifestation was seen in 58.3%.
Neurological involvement appeared in 16.7%. Osteoarticular
manifestations were presents in 75%. HLA class I alleles were
determined in all patients; HLA-B51 was present in two female
patients. Seven patients had familiar history of recurrent oral
ulceration but only 1 with BD. Evolution was marked by one eye
blindness in one female patient with panuveitis.
Downloads
References
Crespo J, Patto V, Proença R: E:Artigos Behçet Portugal.htm. BD News. Epidemiology of Behçet’s Syndrome in Portugal. Portuguese study group for Behçet’s disease (Portugal), 2003.
Hanza M’Hamed. Maladie de Behçet. In : Kahn M, Peltrier A, Meyer O, Piette JC. Maladies et syndromes systémiques : Flammarion 2000:883-924.
International Study Group for Behçet’s Disease. Criteria for diagnosis of Behçet Disease. Lancet 1990;335:1078-1080.
Nussenblatt RB. Uveitis in Behçet’s disease. Int Rev Immunol 1997;14:67-79.
Tsuyoshi S., Mitsuhiro T. Behçet’s Disease. New Engl J Med 1999;341(14):1284-1291.
Monteiro M. Síndroma Óculo-Buco-Genital de Behçet. Bol Soc Oftalmol 1946;5:125-135.
Souza-Ramalho P, d’Almeida M, Freitas J, Pinto J. Incidence and Clinical Aspects of Behçet Disease in Portugal. Behçet Disease – Basic and Clinical Aspects (Marcel Dekker, Inc) 1991;291-298.
Grupo Nacional para o Estudo da Doença de Behçet, Jorge Crespo. Doença de Behçet – Casuística nacional. Medicina interna 1997;4(4):225-232
Additional Files
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2023 Medicina Interna
Open Access
