Longitudinal nutritional evaluation in a population infected with the human immunodeficiency virus
Keywords:
HIV infection, nutrition, bioelectrical impedance analysis, body compositionAbstract
In the belief that body composition changes in HIV-infected
patients begin early in the course of the disease and that such
changes are silent and stage independent, 42 asymptomatic HIV
carriers were evaluated regarding anthropometrics, biochemical
and body composition using bioelectrical impedance analysis
measurements. 35 of these patients completed the two years
follow-up period. Among the parameters studied, the difference
between the initial and the final value was statistically significant
for the CD4 count, serum albumin, phase angle and for the
extracellular mass/body cell mass index. There were no such
differences found for body mass index, lean body mass, and
body cell mass.
The 35 patients were divided in two groups, one with no AIDS
defining event and the other with progression to AIDS. Between
those two groups of patients, there were no statistically significant differences.
It was concluded that a systematic and timely metabolic and
nutritional evaluation allows body composition changes to be
detected, even before they become clinically or biochemically evident.
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