Systemic aortoarteritis: a case review
Keywords:
arteritis, aortoarteritis, Takayasu arteritis, giant cell arteritisAbstract
Systemic aortoarteritis of adults is an uncommon inflammatory disease of uncertain aetiopathogenesis, involving the aorta,
pulmonary and temporal arteries as well as their branches.This
article analyses the case of a 71-year-old man, a native of India,
with symptoms suggestive of an inflammatory or consumptive
disease. Positron emission tomography led to the diagnosis,
demonstrating diffuse abnormal fluorine-18 fluorodeoxyglucose
arterial uptake in the thoracic aorta and in both subclavian
arteries. Magnetic resonance imaging confirmed the diagnosis,
presenting furthermore inflammation of the pulmonary trunk.
Differentiation between Takayasu arteritis and giant cell arteritis
was not definitively possible, considering international established
criteria. Prednisolone therapy resulted in clinical and laboratory
remission. Positron emission tomography control showed total
regression of the disease process. The data of this rare disease
may be helpful for an early diagnosis and treatment as well as
preventing severe vascular complications.
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References
Fietta P. Systemic vasculitides: Immunogenetics and familial clustering. Clin Exp Rheumatol 2004; 22:238-251.
Panja M, Mondal PC. Current Status of Aortoarteritis in India. JAPI 2004; 52: 48-52.
Hellmann DB. Temporal Arteritis. JAMA 2002; 287: 2996-3000.
Mwipatayi BP, Jeffery PC, Beningfield SJ et al. Takakayasu Arteritis: Clinical features and management: Report of 272 cases. ANZ J Surg 2005;
:110-117.
Romera-Villegas A, Vila-Coll R, Poca-Dias V, Cairols-Castellote MA. The role of color duplex sonography in the diagnosis of giant cell arteritis. J Ultrasound Med 2004; 23:1493-1498.
Meller J, Strutz F, Siefker U et al. Early diagnosis and follow-up of aortitis with [18F]FDG PET and MRI. Eur J Nucl Med Mol Imaging 2003; 30:730-736.
Ureten K, Öztürk MA, Onat AM et al. Takaysu’s arteritis: results of a university hospital of 45 patients in Turkey. Int J Cardiol 2004;96:259-264.
Hellmann DB. Immunopathogenesis, diagnosis, and treatment of giant cell arteritis, temporal arteritis, polymyalgia rheumatica, and Takayasu’s arteritis. Curr Opin Rheumatol 1993; 5:25:32.
Tripathy NK, Chauhan SK, Nityanand S. Cytokine mRNA repertoire of perpheral blood mononuclear cells in Takayasu’s arteritis. Clin Exp Immunol 2004; 138:369-374.
Arend WP, Michel BA, Bloch DA et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum 1990; 33:1129-1134.
Rao JK, Allen NB, Pincus T. Limitations of the 1990 American College of Rheumatology classification criteria in the diagnosis of vasculitis. Ann Intern Med 1998; 129:345-352.
Uthman I. Pharmacological therapy of vasculitis: an update. Curr Opin Pharmacol 2004; 4:177-182
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