Kikuchi-Fujimoto disease: a rare cause of cervical Adenopathies
Keywords:
Kikuchi-Fujimoto disease, histiocytic necrotizing lymphadenitisAbstract
Kikuchi-Fujimoto disease, also nominated
histiocytic necrotizing lymphadenitis, was described in 1972 and is characterised by a benign,
self-limiting course and unknown aetiology
affecting predominantly young women in their second or third decades of life.
Clinical features include bilateral cervical lymphadenopathy in association with fever, even
though other constitutional symptoms may be
present. Diagnosis is based on histopathological findings, being important to consider differential diagnosis with infectious, autoimmune and lymphoproliferative lymphadenopathies.
This disease has a good prognosis without
therapy, nevertheless, if necessary, nonsteroid
anti-inflamatory drugs (NSAID’s) or low dose corticosteroids are used.
The authors present a case of a 26 years old
woman with cervical bilateral lymphadenopathies and malaise. The histological result of an
excised lymph node was histiocytic necrotizing
lymphadenitis. Evolution was excellent and
the patient was assymptomatic without any treatment.
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