Novos padrões versus velhos hábitos de prescrição de albumina num hospital central
Palavras-chave:
albumina humanaResumo
O presente estudo teve como objectivo aferir a adequação da
prescrição de albumina humana num hospital central à evidência
científica nesta área actualmente disponível.
O estudo foi retrospectivo e analisou os pedidos de albumina
aos serviços farmacêuticos entre Setembro de 2007 e Agosto
de 2008. Analisadas 761 requisições de 619 doentes com idade
média de 58,1 +/- 14,7 anos, 510 (77%) dos quais do sexo masculino. Foram avaliados parâmetros analíticos globais (proteínas
totais, albumina sérica, creatinina e INR) à data da requisição de
albumina, grandes grupos nosológicos e os motivos de prescrição.
Dos 556.831 frascos de albumina requisitados, foram efectivamente administrados 5.033 (0,9%). Os doentes com patologia
hepática foram o grupo nosológico mais representado (60%).
Verificou-se que 36% dos pedidos correspondiam aos critérios
científicos com suporte de evidência, sendo a hipoalbuminémia
o motivo mais frequente de pedido (53%). Concluímos que é
necessário um maior cuidado no fundamento dos pedidos de
albumina, de forma a adequá-los à evidência científica. Normas
restritivas dos serviços farmacêuticos para o fornecimento de
albumina encontram-se justificadas.
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