Ependimoma intramedular: Revisão da literatura A propósito de um caso clínico
Palavras-chave:
ependimoma intramedular, lombalgiaResumo
A lombalgia é uma queixa muito frequente na prática clínica diária.
Os autores apresentam um caso clínico de lombalgia num homem
de 33 anos, cujo estudo complementar revelou tratar-se de um
ependimoma intramedular com localização D9-L1. O ependimoma
é um dos tumores da glia e constitui a neoplasia intramedular
mais frequente do adulto. Os autores apresentam este caso para
salientar que as neoplasias da medula espinhal, e em particular o
ependimoma, devem ser consideradas no diagnóstico diferencial
dos doentes com dor localizada à coluna vertebral, sobretudo se
apresentarem défices sensoriais ou motores.
A propósito deste caso os autores fazem uma breve revisão
bibliográfica dos ependimomas intramedulares.
Downloads
Referências
Constantini S, Houten J, Miller D et al. Intramedullary spinal cord tumors in children under the age of 3 years. J Neurosurg 1996;85:1036-1043.
Hoshimaru M, Koyama T, Hashimoto N, Kikushi H. Results of microsurgical treatment for intramedullary spinal cord ependymomas: analysis of 36 cases. Neurosurgery 1999;44:264-269.
Epstein FJ, Farmer JP, Freed D. Adult intramedullary spinal cord ependymomas: the result of surgery in 38 patients. J Neurosurg 1993;79:204-209.
Ferrante L, Mastronardi L, Celli P, Lunardi P, Acqui M, Fortuna A. Intramedullary spinal cord ependymomas: a study of 45 cases with long-term follow-up. Acta Neurochir 1992;119:74-79.
Brotchi J, Fischer G. Intramedullary spinal cord tumors. Stuttgart, Germany: Thieme, 1996;60-84.
Lamszus K, Lachenmayer L, Heinemann U, Kluwe L, Finckh U, Hoppner W, Stavron D, Fillbrandt R, Westphal M. Molecular genetic alterations on chromosomes 11 and 22 in ependymomas. Int J Cancer. 2001;91(6):803-808.
Onaya M, Kujas M, Tominaga I, Arthuis F, Marsault C, Poirier J. Intramedullary lipomatous ependymoma: case report. Ann Pathol 2005;25(3):240-243.
Kleinman GM, Zagzag D, Miller DC. Epithelioid ependymoma: a new variant of ependymoma: report of three cases. Neurosurgery 2003;53(3):743-747.
Parsa AT, Fiore AJ, McCormick PC, Bruce JN. Genetic basis of intramedullary spinal cord tumors and therapeutic implications. J Neurooncol.
;47(3):239-251.
Helwig EB, Stern JB. Subcutaneous sacrococcygeal myxopapillary ependymoma: a clinico-pathologic study of 32 cases. Am J Clin Pathol
;81:156-161.
Fassett DR, Scmidt MH. Lumbosacral ependymomas: a review of the management of intradural and extradural tumors. Neurosurg Focus
;15(5):E13.
Shrivastava RK, Epstein FJ, Perin NI, Post KD, Jallo GI. Intramedullary spinal cord tumors in patients older than 50 years of age: management and outcome analysis. J Neurosurg Spine 2005;2(3):249-255.
Koeller KK, Rosenblum RS, Morrison AL. Neoplasms of the spinal cord and filum terminale: radiologic-pathologic correlation. Radiographics 2000;20:1721-1748.
Miyazawa N, Hida K, Iwasaki Y, Koyanagi I, Abe H. MRI at 1.5 T in intramedullary ependymoma and classification of pattern of contrast enhancement. Neuroradiology 2000;42(11):828-832.
Sun B, Wang C, Wang J, Liu A. MRI features of intramedullary spinal cord ependymomas. J Neuroimaging 2003;13(4):346-351.
Wilmshurst JM, Barrington SF, Pritchard D, Cox T, Bullock P, Maisey M, Robinson RO. Positron emission tomography in imaging spinal cord tumors. J Child Neurol. 2000;15(7):465-472.
Peet AC, Leach MO, Pinkerton CR, Price P, Williams SR, Grundy RG. The development of functional imaging in the diagnosis, management and understanding of childhood brain tumors. Pediatr Blood Cancer 2005;44(2):103-113.
Schwartz TH, McCormick PC. Intramedullary ependymomas: clinical presentation, surgical treatment strategies and prognosis. J Neurooncol 2000;47(3):211-218
Ryu SI, Kim DH, Chang SD. Stereotactic radiosurgery for hemangiomas and ependymomas of the spinal cord. Neurosurg Focus 2003;15(5):E10.
Peker S, Ozgen S, Ozek MM, Pamir MN. Surgical treatment of intramedullary spinal cord ependymomas: can outcome be predicted by tumor parameters? J Spinal Disrd Tech. 2004;17(6):516-521.
Chang UK, Choe WJ, Chung SK, Chung CK, Kim HJ. Surgical outcome and prognostic factor of spinal intramedullary ependymomas in adults. J Neurooncol. 2002;57(2):133-139.
Isaacson SR. Radiation therapy and the management of intramedullary spinal cord tumors. J Neurooncol. 2000;47(3):231-238.
Witaker SJ, Bessel EM, Ashley SE et al. Postoperative radiotherapy in the management of spinal cord ependymoma. J Neurosurg. 1992;74:720-728.
Wen CB, Hussey DH, Hitchon PW et al. The role of radiation therapy in the management of ependymomas of the spinal cord. Int J Radiat Oncol Biol Phys 1991;20:781-786.
Balmaceda C. Chemotherapy for intramedullary spinal cord tumors. J Neurooncol. 2000;47(3):293-307.
Chamberlain MC. Recurrent intracranial ependymoma in children: salvage therapy with oral etoposide. Pediatr Neurol 2001;24:117-121.
Needle MN, Molloy PT, Geyer JR et al. Phase 2 study of daily oral etoposide in children with recurrent brain tumors and other solid tumors. Med Pediatr Oncol 1997;29:28-32.
Robertson PL, Zeltzer PM, Boyeyy JM et al. Survival and prognostic factors following radiation therapy for ependymomas in children : a report on the Children’s Cancer Group. J Neurosurg 1998;88:685-703.
Duffner PK, Krischer JP, Sanford RA et al. Prognostic factors in infants and very young children with intracranial ependymomas. Pediatr Neurosurg 1998;28:215-222.
Grill J, Kalifa C, Doz F et al. A high dose busulfan-thiotepa combination followed by autologous bone marrow transplantation in childhood recurrent ependymoma. A phase 2 study. Pediatr Neurosurg 1996;25:7-12.
Mason WP, Goldman S, Yates AI, Boyett J, Li H, Faly JL. Survival following intensive chemotherapy with bone marrow reconstitution for children with recurrent intracranial ependymoma: a report of Children’s Cancer Group. J Neurooncol 1998;37:135-143.
Allen JC, Aviner S, Yates AJ et al. Treatment of high-grade spinal cord astrocytomas of childhood with “8-in-1” chemotherapy and radiotherapy: a pilot study of CCG-945. J Neurosurg 1998;88:215-220.
Chamberlain MC. Salvage chemotherapy for recurrent spinal cord ependymoma. Cancer 2002;95:997-1002.
Sandalcioglu IE, Gasser T, Asgari S, Lazorisak A, Engelhorn T, Egelhof T, Stolke D, Wiedemayer H. Functional outcome after surgical treatment of intramedullary spinal cord tumors: experience with 78 patients. Spinal Cord
;43(1):34-41
Ficheiros Adicionais
Publicado
Como Citar
Edição
Secção
Licença
Este trabalho encontra-se publicado com a Licença Internacional Creative Commons Atribuição 4.0.
Direitos de Autor (c) 2023 Medicina Interna
Acesso livre
