Complicações/Sequelas Pós-Infeção por SARS-CoV-2: Revisão da Literatura

Autores

  • Maria da Luz Brazão Assistente Graduada Sénior de Medicina Interna, Núcleo de Estudos de Urgência e do doente Agudo da SPMI/ Serviço de Medicina Interna do Hospital Central do Funchal, SESARAM-EPERAM, Funchal, Portugal https://orcid.org/0000-0002-2584-1573
  • Sofia Nóbrega Assistente Hospitalar de Medicina Interna, Núcleo de Estudos de Urgência e do doente Agudo da SPMI/Serviço de Medicina Interna do Hospital Central do Funchal, SESARAM-EPERAM, Funchal, Portugal https://orcid.org/0000-0003-3433-3105

DOI:

https://doi.org/10.24950/R/MLBrazao/SNobrega/2/2021

Palavras-chave:

Infecções por Coronavírus/complicações, COVID-19/complicações, SARS-CoV-2

Resumo

A doença COVID-19 surgiu em dezembro de 2019 e desde então disseminou-se por todo o mundo, obrigando à adaptação de estruturas e reorganização de serviços hospitalares, e colocando à classe médica o grande desafio de em tempo recorde, se atualizar e se manter em constante aprendizagem. Para os sobreviventes desta doença, a eliminação do vírus SARS-CoV-2, é apenas o começo de um caminho de recuperação incerto e desconhecido. De facto, segundo o conhecimento atual, o que se segue à fase aguda da infeção por SARS-CoV-2 depende da extensão e gravidade da invasão viral nos diferentes tipos de células e órgãos, mas apesar do número crescente de artigos publicados no último ano, ainda não existe uma descrição inequívoca, de um quadro clínico típico das consequências da COVID-19. Com o objetivo de conhecer o estado da arte sobre este tema, as autoras fazem uma revisão do que tem sido publicado sobre complicações/sequelas da infeção por SARS-CoV-2.

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Referências

Gemelli Against COVID-19 Post-Acute Care Study Group. Post‑COVID‑19 global health strategies: the need for an interdisciplinary approach. Aging Clin Exp Res. 2020;32:1613-20. doi: 10.1007/s40520-020-01616-x.

Munhoz RP, Pedroso JL, Nascimento FA, Almeida SM, Barsottini OP, Cardoso FC, et al. Neurological complications in patients with SARS-CoV-2 infection: a systematic review. Arq Neuropsiquiatr. 2020;78:290-300. doi: 10.1590/0004-282x20200051.

Tumlinson A, Altman W, Glaudemans J, Gleckman H, Grabowsk DC. Post-Acute Care Preparedness in a COVID-19 World. J Am Geriatr Soc.

;68:1150-54. doi: 10.1111/jgs.16519.

Logue JK, Franko NM, McCulloch DJ, McDonald D, Magedson A, Wolf CR, et al. Sequelae in Adults at 6 Months After COVID-19 Infection. JAMA Netw Open. 2021;4:e210830. doi: 10.1001/jamanetworkopen.2021.0830.

Carvalho-Schneider C, Laurent E, Lemaignen A, Beaufils E, Bourbao-Tournois C, Laribi S, et al. Follow-up of adults with noncritical COVID-19

two months after symptom onset. Clin Microbiol Infect. 2021;27:258-263. doi: 10.1016/j.cmi.2020.09.052.

Dani M, Dirksen A, Taraborrelli P, Torocastro M, Panagopoulos D, Sutton R, et al. Autonomic dysfunction in ‘long COVID’: rationale, physiology

and management strategies. Clin Med. 2021;21:e63-e67. doi: 10.7861/clinmed.2020-0896.

Dicpinigaitis PV, Canning BJ. Is There (Will There Be) a Post-COVID-19 Chronic Cough? Lung. 2020;198:863-5. doi: 10.1007/s00408-020-00406-6.

Ayoubkhani D, Khunti K, Nafilyan V, Maddox T, Humberstone B, Diamond I, et al. Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study. BMJ. 2021;372:n693. doi:10.1136/bmj.n693.

Landi F, Barillaro C, Bellieni A, Brandi V, Carfi A, D’Angelo M, et al. The New Challenge of Geriatrics: Saving Frail Older People from the SARS-CoV-2 Pandemic Infection. J Nutr Health Aging. 2020;24:466-70. doi:10.1007/s12603-020-1356-x.

Woodruff A. COVID-19 Follow up Testing. J Infect. 2020;81:647-79. doi: 10.1016/j.jinf.2020.05.012.

Ward H, Atchison C, Whitaker M, Ainslie KEC, Elliott J, Okell L, et al. Antibody prevalence for SARS-CoV-2 in England following first peak of the

pandemic: REACT2 study in 100 000 adults. medRxiv [Preprint] 2020. https://www.medrxiv.org/content/10.1101/2020.08.12.20173690v2.

Figueiredo-Campos P, Blankenhaus B, Mota C, Gomes A, Serrano M, Ariotti S, et al. Seroprevalence of anti-SARS-CoV-2 antibodies in COVID-19 patients and healthy volunteers up to 6 months post disease onset. Eur J Immunol. 2020; 50: 2025–40. doi: 10.1002/eji.202048970.

McDonald LT. Healing after COVID-19: are survivors at risk for pulmonary fibrosis? Am J Physiol Lung Cell Mol Physiol. 2021;320:L257-L265.

Shaw B, Daskareh M, Gholamrezanezhad A. The lingering manifestations of COVID‑19 during and after convalescence: update on long‑term

pulmonary consequences of coronavirus disease 2019 (COVID‑19). Radiol Med. 2021;126:40-6. doi: 10.1007/s11547-020-01295-8.

Wang F, Kream RM, Stefano GB. Long-Term Respiratory and Neurological Sequelae of COVID-19. Med Sci Monit. 2020;26:e928996. doi:10.12659/MSM.928996.

Halpin SJ, McIvor C, Whyatt G, Adams A, Harvey O, McLean L, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol. 2021;93:1013-22. doi: 10.1002/jmv.26368.

Wostyn P. COVID-19 and chronic fatigue syndrome: Is the worst yet to come? Med Hypotheses. 2021;146:110469. doi: 10.1016/j.mehy.2020.110469.

Sutherland S. Mysteries of COVID-19 smell loss finally yield some answers. Scientific American. 2020 [consultado 2021 Mar 5]. Disponível

em: https://www.scientificamerican.com/article/mysteries-of-covid-smell-loss-finally-yield-some-answers1/.

Taquet M, Geddes JR, Husain M, Luciano S, Harrison PJ. 6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-

: a retrospective cohort study using electronic health records. Lancet. 2021;8:416-27. doi: 10.1016/S2215-0366(21)00084-5

Cortinovis M, Perico N, Remuzzi G. Long-term follow-up of recovered patients with COVID-19. Lancet. 2021;397:173-5. doi: 10.1016/S0140-6736(21)00039-8.

Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021; 397: 220–32. doi: 10.1016/S0140-6736(20)32656-8.

Wijeratne T, Crewther S. Post-COVID 19 Neurological Syndrome (PCNS); a novel syndrome with challenges for the global neurology community. J Neurol Sci. 2020;419:117179. doi: 10.1016/j.jns.2020.117179.

Sayed SE, Shokry D, Gomaa SM. Post-COVID-19 fatigue and anhedonia: A cross-sectional study and their correlation to post-recovery period.

Neuropsychopharmacol Rep. 2021;41:50-5. doi: 10.1002/npr2.12154.

Davido B, Seang S, Barizien N, Tubiana R, Truchis P. 'Post-COVID-19 chronic symptoms' - Author's reply. Clin Microbiol Infect. 2021;27:495-

doi: 10.1016/j.cmi.2020.09.001.

Taquet M, Luciano S, Geddes JR, Harrison PJ. Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA. Lancet Psychiatry. 2021; 8: 130–40. doi: 10.1016/S2215-0366(20)30462-4.

Barker-Davies RM, O’Sullivan O, Senaratne KPP, Baker P, Cranley M, Dharm-Datta S, et al. The Stanford Hall consensus statement for post-COVID-19 rehabilitation. Br J Sports Med. 2020;54:949–59. doi:10.1136/bjsports-2020-102596.

Tajbakhsh A, Hayat SMG, Taghizadeh H, Akbari A, Inabadi, Savardashtaki A, et al. COVID-19 and cardiac injury: clinical manifestations, biomarkers, mechanisms, diagnosis, treatment, and follow up. Expert Rev Anti Infect Ther. 2021;19:345-57. doi: 10.1080/14787210.2020.1822737.

Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021;27:601-15.

doi: 10.1038/s41591-021-01283-z

Candan SA, Elibol N, Abdullahi A. Consideration of prevention and management of long-term consequences of post-acute respiratory distress

syndrome in patients with COVID-19. Physiother Theory Pract. 2020;36:663-8. doi: 10.1080/09593985.2020.1766181.

Asly M, Hazim A. Rehabilitation of post-COVID-19 patients. Pan Afr Med J. 2020;36:168. doi: 10.11604/pamj.2020.36.168.23823.

Balachandar V, Mahalaxmi I, Subramaniam M, Kaavya J, Kumar NS, Laldinmawii G. Follow-up studies in COVID-19 recovered patients - is it

mandatory? Sci Total Environ. 2020;729:139021. doi: 10.1016/j.scitotenv.2020.139021.

Rofle RJ, Smith CM, Wolfe CR. The Emerging Chronic Sequelae of COVID-19 and Implications for North Carolina. N C Med J. 2021;82:75-

doi: 10.18043/ncm.82.1.75.

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Publicado

18-06-2021

Como Citar

1.
Brazão M da L, Nóbrega S. Complicações/Sequelas Pós-Infeção por SARS-CoV-2: Revisão da Literatura. RPMI [Internet]. 18 de Junho de 2021 [citado 17 de Novembro de 2024];28(2):184-9. Disponível em: https://revista.spmi.pt/index.php/rpmi/article/view/65

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