Schmidt’s syndrome – a clinical case

Authors

  • José N. Raposo Interno do Internato Complementar de Medicina Interna, Serviços de Medicina e Endocrinologia do Hospital Garcia de Orta, Lisboa
  • Susana Sousa Interna do Internato Complementar de Pneumologia, Hospital Garcia de Horta, Almada, Portugal
  • João Namora Assistente Hospitalar Graduado de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal
  • Aurora Tomaz Assistente Hospitalar Graduada de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal
  • Luísa Raimundo Assistente Hospitalar Graduada de Endocrinologia, Hospital Garcia de Orta, Almada, Portugal
  • Carlos Fernandes Assistente Hospitalar de Endocrinologia, Hospital Garcia de Orta, Almada, Portugal
  • José M. Ferreira Chefe de Serviço de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal

Keywords:

Addison disease, polyglandular autoimmune syndrome

Abstract

A 43-year-old woman was admitted because of
nausea, vomiting, weakness and weight loss. On
examination hypotension and cutaneous hyperpigmentation were detected. The sodium level
was very low. Those findings suggested adrenal failure. The diagnosis of Addison disease was
made because of low levels of cortisol and high levels of adrenocorticotropic hormone. Mild elevation of thyroid-stimulating hormone, normal levels of free thyroxine and free iodothyronine,
associated to high levels of antithyroid antibodies, suggested chronic lymphocytic thyroiditis.
The association beteween Addison disease and autoimmune thyroid disease is the hallmark of Schmidt’s syndrome. The patient showed a positive evolution after the beginning of glucocorticoid replacement therapy.

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Additional Files

Published

2004-12-31

How to Cite

1.
N. Raposo J, Sousa S, Namora J, Tomaz A, Raimundo L, Fernandes C, Ferreira JM. Schmidt’s syndrome – a clinical case. RPMI [Internet]. 2004 Dec. 31 [cited 2024 Nov. 23];11(4):183-6. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1764

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