Hepatites tóxicas: revisão da literatura


  • Luís Costa Matos Serviço de Medicina 1 do Hospital de São Teotónio S.A., Viseu
  • Borges Martins Serviço de Medicina 1 do Hospital de São Teotónio S.A., Viseu


Hepatite tóxica, hepatite medicamentos


Considera-se hepatite tóxica a lesão hepática causada por
agentes farmacológicos ou químicos, e deve ser considerada
como diagnóstico diferencial na abordagem inicial de patologia
hepática. Os autores apresentam uma revisão da literatura sobre
este tema, abordando a fi siologia da metabolização hepática, factores de risco e predisposição para hepatotoxicidade, critérios de
diagnóstico, quadros clínicos e laboratoriais, fazendo em seguida
referência a vários fármacos classicamente hepatotóxicos, bem
como a medicamentos mais recentes, excipientes e produtos ditos
“naturais”, algumas vezes causadores de lesão hepática.


Não há dados estatísticos.


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Costa Matos L, Martins B. Hepatites tóxicas: revisão da literatura. RPMI [Internet]. 30 de Dezembro de 2005 [citado 7 de Dezembro de 2023];12(4):239-58. Disponível em: https://revista.spmi.pt/index.php/rpmi/article/view/1712



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