Bartonella endocarditis: a culture-negative endocarditis clinical case report

Authors

  • Aida Cordeiro Servico de Medicina Interna do Hospital Santa Luzia de Elvas
  • Vera Escoto Servico de Medicina Interna do Hospital Santa Luzia de Elvas
  • Luísa Lopes Servico de Medicina Interna do Hospital Santa Luzia de Elvas

Keywords:

Endocarditis, Bartonella, Culture-negative endocarditis

Abstract

The diagnosis of infectious endocarditis is based on identification
of the causal agent and evidence of valvular alterations seen on
cardiac ultrasound. Cases of culture- negative endocarditis are a
clinical challenge, because they present frequently with a subacute
or chronic evolution and need other techniques for detection of the causative microorganism.
Bartonella sp. is an increasingly more frequent cause of
culture- negative endocarditis, and the diagnosis is based on an
epidemiological history and serological tests.
The authors present a case of a woman with a prosthetic valve
and several months history of fever and pancytopaenia, with negative cultures and serology positive for Bartonella spp.
A revision of the approach for diagnosis of the culturenegative endocarditis, specifically cases due to Bartonella sp.,
is reported.

Downloads

Download data is not yet available.

References

Breitkopf C, Hammel D, Scheld H, Peters G, Becker K. Impact of a Molecular Approach to Improve the Microbiological Diagnosis of Infective Heart Valve Endocarditis. Circulation 2005;111:1415-1421.

Dhawan VK. Infective endocarditis in elderly patients. Clin Infect Dis. 2002; 34:806-812.

Wallace SM, Walton BI, Kharbanda RK, Hardy R, Wilson AP, Swanton RH. Mortality from infective endocarditis: clinical predictors of outcome: Heart 2002; 88:53-60.

Millar B, Moore J. Emerging Issues in Infective Endocarditis. Emerging Infectious Diseases 2004; 10:1110-1116.

The Task Force on Infective Endocarditis of European Society of Cardiology. Guidelines on Prevention, Diagnosis and Treatment of Infective Endocarditis. Euroean Heart Journal 2004; 00:1-37.

Karchmer AW. Endocarditis Infecciosa. In Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, eds. Harrison. Principios de Medicina Interna. 16ª edición. McGraw-Hill 2006:820-830.

Biddinguer P, Isselbacher E, Fan D, Shepard J. Case-2005: A 53-Year-Old Man with Depression and Sudden shortness of Breath. N Engl J Med 2005; 352:709-716.

Brouqui P, Raoult D. Endocarditis Due to Rare and Fastidious Bacteria. Clin Microbiol Rev 2001;14(1):177-207.

Mann P, Nye F, Williams G, Walker A, Amadi A. From trench fever to endocarditis. Postgrad Med J 2003; 79:655-656.

Delgado M, Castillo JC, Anguita M Mesa D. Endocarditis en situaciones especiales, anciano, portador de prótesis, endocarditis con hemocultivo negativo. Medicine 2005; 9(43):2834-2840.

Raoult D, Fournier PE, Drancourt M et al. Diagnosis of 22 new cases of Bartonella endocarditis. Ann Intern Med 1996;125:646-652.

Blanco JR, Raoult D. Enfermedades producidas por Bartonella spp. Enferm Infecc Microbiol Clin 2005; 23(5):313-320.

Tsukahara M, Tsuneoka H, Iino H, Murano I, Takahashi H, Uchida M. Bartonella henselae Infection as a Cause of Fever of Unknown Origin. J Clin Microbiol 2000;38:1990-1991.

Spach D, Kanter A, Dougherty M et al. Bartonella (Rochalimaea) quintana bacteriemia in inner-city patients with chronic alcoholism. N Engl J Med 1995;332:424-428.

Goldstein L, Saliba W, Elias M, Zlotnik A, Raz R, Giladi M. Bartonella quintana endocarditis in East Africa. Eur J Intern Med 2005;16:518-519

Additional Files

Published

2008-09-30

How to Cite

1.
Cordeiro A, Escoto V, Lopes L. Bartonella endocarditis: a culture-negative endocarditis clinical case report. RPMI [Internet]. 2008 Sep. 30 [cited 2024 Nov. 17];15(3):186-91. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1475

Issue

Section

Case Reports