Reninoma: a rare cause of arterial hypertension
Keywords:
Reninoma, juxtaglomerular cell tumour, hypertensionAbstract
Juxtaglomerular cell tumours, also called reninomas, are benign and rare causes of secondary
high blood pressure.
The authors present a case of a 19-year-old
woman, admitted to the Coimbra University
Hospitals Department of Medicine, suffering
from high blood pressure of recent onset.
Laboratory fi ndings revealed a decrease in
serum potassium and an increased plasma
renin and plasma aldosterone level. The abdominal magnetic resonance scan revealed a mass
in the right kidney, in its middle portion. The
right renal artery angiography confi rmed the
topographic localization, as well as the poor vascularization of the mass.
In the presence of these fi ndings, the patient
was proposed for surgery, which was successfully performed without any complications (a
parenquimal-sparing excision of the tumour was performed).
The histological study of the tissue excised revealed a reninoma.
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References
Robertson PW, Klidjian A, Harding LK, Walters G. Hypertension due to a rennin-secreting renal tumor. Am J Med 1967; 43: 963.
Lam AS, Bédard YC, Buckspan MB, Logan AG, Steinhardt MI. Surgically curable hypertension associated with reninoma. J Urol 1982;
(3): 572-575.
Vaughan ED. Renal and adrenal sparing surgery for patients with primary aldosteronism and primary reninoma. J Urol 1995; 153 (6): 1785-6.
Hanna W, Tepperman B, Lagan Ag, Robinette MA, Colapinto R, Phillips MJ. Juxtaglomerular cell tumors (reninoma) with paroxysmal
hypertension. Can Med Assoc J 1979; 120 (8): 957-959.
Haab F, Duclos JM, Guyenne T, Plonin PF, Corvol P. Renin secreting tumors: diagnosis, conservative surgical approach and long-term
results. J Urol 1995; 153: 1781-1784.
Dennis RL, McDougal WS, Glick AD, MacDonell Jr RC. Juxtaglomerular cell tumor of the kidney. J Urol 1985; 134: 334-348.
Eddy RL, Sanchez SA. Renin-secreting renal neoplasm and hypertension with hypokalemia. Ann Intern Med 1971; 75: 725.
Conn JW, Cohen EL, Lucas CP, McDonald WJ, Mayor GH, Blongh WM et al. Primary reninism. Hypertension, hyperreninemia and secondary
aldosteronism due to renin-producing juxtaglomerular cell tumor. Arch Intern Med 1972; 130: 682.
Brown JJ, Fraser R, Lever AF, Morton JJ, Robertson JS, Tree M et al. Hypertension and secondary hyperaldosteronism associated with
a renin-secreting renal juxtaglomerular cell tumor. Lancet 1973; 2: 1228.
El Matri A, Ben Ayed H, Slim R, Ben Maiz H, Zmerli S et al. Un autre cas d’hypertension artérielle due à une tumeur de l’appareil juxta-glomérulaire. J d’Urol 1980;86:33
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