Splenic hamartoma with haematologic disorders

Authors

  • J. Bernardes Correia Assistente Hospitalar de Medicina Interna, Hospitais da Universidade de Coimbra
  • Benilde Barbosa Interna do Internato Complementar de Medicina lnterna, Hospitais da Universidade de Coimbra
  • Bruno Rodrigues Interno do Internato Complementar de Neurologia, Hospitais Universidade de Coimbra
  • Henrique Ferrão Assistente Hospitalar de Cirurgia Geral, Hospitais Universidade de Coimbra
  • João Correia Assistente Hospitalar de Medicina Interna, Hospital da Guarda
  • Fernando Martinho Director do Serviço de Cirurgia II, Hospitais Universidade de Coimbra
  • Fernando Santos Chefe de Serviço de Medicina Interna dos Hospitais da Universidade de Coim­bra
  • Maria Helena Saldanha Directora do Serviço de Medicina I, Hospitais da Universidade de Coimbra

Keywords:

splenic hamartoma, haematologic disorders

Abstract

Hamartomas of the spleen are rare benign tumour­ like lesions composed mainly of vascular elements. Most of them, remain small in size and asymptomatic, and are therefore, incidental findings at laparotomy or autopsy. However, occasionally, they present with symptoms among wich, haematologic disorders appear in a very few cases.

The authors report a case of splenic hamartoma in a 44-year-old woman with pancytopenia. Prolonged enhancement on post-contrast CT and MR imaging was a useful finding in differentiation of splenic hamartoma from malignant lesions of the spleen. Hamartomas should be kept in mind in the differential diagnosis of splenic tumors. Splenectomy, is indicated in cases where malignancy cannot be excluded and in cases of associated haematologic disorders. The haematologic abnormalities, disapeared after removal of the spleen.

By review of the literature, they are less than two tens of well-documented cases of symptomatic splenic hamartomas associated with haematologic disorders.

Downloads

Download data is not yet available.

References

Conceição AS, Martins 1, Gonçalves M, Conceição CM, Carvalho R. Angiossarcoma do Baço. Acta Méd Port 1994;7:697-700.

Medeiros A, Milheiro A, Sousa FC. Patologia esplénica pouco frequente - A propósito de seis casos clínicos. Rev Gastenterol Cir 1995; 12(58):67- 78.

Silverman ML, Liviolsi. Splenic hamartoma. Am J Clin Pathol I 978;70:224-229.

Ohtomo K, Fukuda H, Mori K, Minami M, ltai Y, lnoue Y. CT and MR appearances of splenic hamartoma. J Comput Assist Tomogr 1992; 16(3):425-428.

Zissin R, Lishner M, Athaus V. Case report unusual presentation of splenic hamartoma, computed tomography and ultrasonic findings. Clin Radial 1992;45 (6):410-411.

Wirbel RJ, Uhlig U, Futterer KM. Case report: splenic hamartoma with hematologic disorders. Am J Med Sci 1996;311(5):243-246.

Fujii T, Obara T, Shudo R, Tanno S, Maguchi H, Saitoh Y, Ura H, Kohgo Y. Splenic hamartoma associated with thrombocytopenia. J Gastroenterol 1997;32(1 ): 1 14-118.

Nerlich A, Permanetter W. Fine needle aspiration cytodiagnosis of epidermoid cysts of the spleen: report of two cases. Acta Cytol 1991;35:567-569.

Norowitz DG, Morehouse HT. lsodense splenic mass: hamartoma a case report. Comp Med lmaging Graph 1989; 13 (4):347-350.

Thompson SE, Walsh EA, Cramer BC, Pushpanathan CC, Hollett P, Ingram L, Price D. Radiological features of a symptomatic splenic hamartoma. Pediatr Radial l996;26:57-60.

Ohta H, Komibuchi T, Kondo S, Yoshida M, Yamamoto S, Ukikusa M, Awane H, Tomono N, Shintaku M. 99mTc-DTPA-HSA uptake in a case of splenic hamartoma. Ann Nucl Med 1996;10:449- 451.

Kumar PV. Splenic hamartoma. A diagnostic problem on fine needle aspiration cytology. Acta Cytol 1995;39:391-395.

Ramani M, Reinhold C, Semelka RC, Siegelman ES, Liang L, Ascher SM, Brown JJ, Eisen RN, Bret PM. Splenic hemangiomas and hamartomas: MR imaging characteristics of 28 lesions. Radiology 1997;202: 166-172.

Narita T, Hizawa Y. Lymphangiomatous hamartoma of the spleen. Pathol Res Pract 1995; 191:1165-1167

Morgenstern L, McCafferty L, Rosenberg J, Michel SL. Hamartoma of the spleen, Archives of Surgery 1984;119:1291- 1293.

Iakovidou J, Panayiotides J, Papacharalambous X, Farfarellos C. Splenic hamartoma: a case report. Eur J Surg Oncol 1995:21:688- 690.

Soderstrom N. How to use cytodiagnostic spleen puncture. Acta Med Scand 1976 ;199:1-5.

Beham A, Herman W, Vennigerholz F, Schmid C. Hamartoma of the spleen with hematological symptoms. Virchows Arch A Pathol Anat Histopathol 1989; 414:535-539.

lozzo RV, Hass JE, Chard RL. Symptomatic splenic hamartoma: A report of two cases and revew of the literature. Pediatrics 1980 ;66:261-265.

Bruyn GAW, van Furth R. Pneumococcal polysaccaride vaccines: indications, efficacy and recomendations. Eur J Clin Mocrobiol lnfect Dis 1991; 10(11):897-810.

Lipsky BA, Boyko EJ, Inui TS et al. Risk factors for acquiring pneumococcal infections. Arch Intern Med 1986;146:2179-2185.

Additional Files

Published

1999-03-31

How to Cite

1.
Bernardes Correia J, Barbosa B, Rodrigues B, Ferrão H, Correia J, Martinho F, Santos F, Saldanha MH. Splenic hamartoma with haematologic disorders. RPMI [Internet]. 1999 Mar. 31 [cited 2024 Dec. 18];6(1):50-3. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2040

Issue

Vol. 6 No. 1 (1999): Janeiro/ Março

Section

Case Reports

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2023 Medicina Interna

Open Access

Most read articles by the same author(s)

1 2 3 > >>