Osteoporosis and HIV infection: what is the connection?
Keywords:
osteoporosis, human immunodeficiency virusAbstract
Osteoporosis is the most common bone dtisease in adults, characterised by the loss of bone mass. Secondary causes are predominant in the male sex. We studied a case of osteoporosis in a 32-year-old male, former drug addict (heroin), with positive serology for HIV I and HCV. The diagnosis of osteoporosis was confirmed by radiologica densitometric, scintigrapbic and histological exams. Secondary causes were excluded. Bone biopsy showed osteopenia with reduction in the number and diameter of trabeculae, and reduction of the osteoid deposit compatible with the diagnosis of a dynamic osteopathy.
This case allows us to speculate about the possible correlation between the immunological alterations verified in HIV infection and the alterations of bone metabolism.
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