Lipoprotein (a) as a cause of statin-resistance: how to treat? – Case report

Authors

  • Carolina Négrier Lourenço Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Marta Rebelo Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Elsa Gaspar Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Diniz Vieira Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • José Manuel Silva Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • J. J. Alves de Moura Serviço de Medicina II dos Hospitais da Universidade de Coimbra

Keywords:

Lipoprotein (a), LDL-cholesterol, cardiovascular risk, nicotinic acid

Abstract

Lipoprotein (a) (Lp(a)) is considered to be a cardiovascular risk
factor, and nicotinic acid is the only available drug that reduces its levels.
The authors present the case of a 44-year-old male patient with
hypercholesterolemia that responded poorly to statin therapy. After
identifying elevated Lp(a) levels combined therapy with nicotinic
acid was initiated, resulting in normalization of LDL-cholesterol
levels. The authors also make a theoretical review of Lp(a) and
nicotinic acid.

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References

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Additional Files

Published

2009-03-31

How to Cite

1.
Négrier Lourenço C, Rebelo M, Gaspar E, Vieira D, Silva JM, Alves de Moura JJ. Lipoprotein (a) as a cause of statin-resistance: how to treat? – Case report. RPMI [Internet]. 2009 Mar. 31 [cited 2024 May 18];16(1):22-6. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1380

Issue

Vol. 16 No. 1 (2009): Janeiro/ Março

Section

Case Reports

License

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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