The value of abdominal fat biopsy in the diagnostic search for amyloid substance

Authors

  • Margarida Ascensão Interna do Internato Complementar de Medicina Interna, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Helena Figueiredo Assistente Hospitalar de Medicina Interna, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Francisco Parente Assistente Hospitalar de Medicina Interna, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Rita Matos Interna do Internato Complementar de Anatomia Patológica, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Borges Alexandrino Assistente Graduado de Medicina Interna, Serviço de Medicina II dos Hospitais da Universidade de Coimbra
  • Políbio Serra e Silva Director de Serviço, Serviço de Medicina li dos Hospitais da Universidade de Coimbra

Keywords:

systemic amyloidosis, abdominal fat biopsy, diagnosis, potassium permanganate

Abstract

Considering their interest in amyloidosis, particu­ larly of lhe primary type (AL), and the results descri­bed in the literature, that indicate a high sensitivity yield in the localization of amyloid substance in ab­dominalfat biopsy, the authors developed and appli­ed this technique, particularly after 1990.

They analyse the results obtained from forty-eight patients submitted to this study by abdominal subcu­taneous fat biopsy, appreciating the technique sensi­tivity and specificity and dedicating special attention to the criteria that lead to its execution. Also they dis­cuss the vahle of the potassium permanganate test.

With this work, thea uthors wish to communicate their experience and evahlate the criteria for theamyloid substance search, contributing to the increase in diag­nosis of amyloidosis by use of a simple technique.

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Additional Files

Published

1997-09-30

How to Cite

1.
Ascensão M, Figueiredo H, Parente F, Matos R, Alexandrino B, Serra e Silva P. The value of abdominal fat biopsy in the diagnostic search for amyloid substance. RPMI [Internet]. 1997 Sep. 30 [cited 2024 May 19];4(3):168-73. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2227

Issue

Vol. 4 No. 3 (1997): Julho/ Setembro

Section

Original Articles

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