Lymphangioleiomyomatosis in a Post-Menopausal Woman
DOI:
https://doi.org/10.24950/rspmi.804Keywords:
Hormone Replacement Therapy, Lymphangioleiomyomatosis, Menopause, PostmenopauseAbstract
Lymphangioleiomyomatosis is a rare disease of unknown etiology
that mainly affects fertile age women, being extremely rare in
post-menopausal women. It is usually associated with hormone
replacement therapy. The authors report a clinical case of a 62
year-old woman who was referenced to medical consultation
due to dyspnea, cough and wheezing for several months. The
patient had a history of spontaneous pneumothorax in 1994
and in menopause since 52 years-old, having already been
submitted to hormone replacement therapy. Objective examination
presented respiratory failure. Complementary exams
reported moderate obstructive ventilatory syndrome and low
carbon monoxide diffusion capacity. CT scan showed multiple
cystic lesions in the lower two-thirds of both lung fields. Surgical
biopsy lung was performed, whose histology and immunohistochemistry
was compatible with lymphangioleiomyomatosis.
The authors present this case due to the rarity of this disease in
post-menopausal women.
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