Anemia das doenças crónicas

Autores

  • Gabriela Sousa Interna do Internato Complementar de Oncologia Médica, Serviço de Medicina Interna do Centro Hospitalar de Coim­ bra
  • Teresa Alfaiate Interna do Internato Complementar de Medicina Interna, Serviço de Medicina Interna do Centro Hospitalar de Coim­bra
  • Mário Rui Ferreira Chefe de Serviço de Medicina Interna, Serviço de Medicina Interna do Centro Hospitalar de Coim­bra
  • Teresa Carvalho Interna do Internato Complementar de Oncologia Mé­dica, Serviço de Medicina Interna do Centro Hospitalar de Coim­bra
  • António Veiga e Moura Assistente Hospitalar de Medicina Interna, Serviço de Medicina Interna do Centro Hospitalar de Coim­bra

Palavras-chave:

anemia, doença crónica, macrófagos, interleuquinas, patogenia, eritropoietina

Resumo

Os autores revêem e discutem os progressos e conceitos actuais de um grupo de anemias que acompanham uma variedade de doenças crónicas e, por isso, é denominado "Anemia das Doenças Crónicas".

O interesse deste tipo de anemias advém do facto de ser a principal causa de anemia em doentes hospitalizados e do seu tratamento passar pela resolução da doença subjacente.

O principal mecanismo patogénico é o bloqueio na reutilização do ferro hematínico, que é provocado pela libertação de interleuquinas e outros mediadores de inflamação, em resposta à lesão tecidular crónica.

Em termos de diagnóstico diferencial, o problema coloca-se com a anemia por défice de ferro, da qual deve ser distinguida, dadas as diferentes condutas terapêuticas.

Analizaremos, ainda, as possibilidades terapêuticas da eritropoietina.

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Publicado

30-09-1999

Como Citar

1.
Sousa G, Alfaiate T, Ferreira MR, Carvalho T, Veiga e Moura A. Anemia das doenças crónicas. RPMI [Internet]. 30 de Setembro de 1999 [citado 17 de Julho de 2024];6(3):190-6. Disponível em: https://revista.spmi.pt/index.php/rpmi/article/view/2074

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