Secundary Diabetes Mellitus, the tip of the iceberg: a report of two clinical cases
Keywords:
Secondary diabetes mellitus, acromegaly, Cushing’s syndrome, adrenocortical carcinomaAbstract
We describe two rare cases of secondary Diabetes Mellitus associated with a GH-secreting pituitary macroadenoma and to a
unilateral cortisol-secreting adrenal tumour. The patients were
admitted in the emergency room, before the endocrine diagnosis
had been made, because of acute complications associated with
diabetes. The clinical presentation of the first patient (Acromegaly)
was serious hyperglycaemia and an increased plasma osmolality.
The second case, an adrenal carcinoma, was an uncommon type
of Cushing’s syndrome, with acute insulin-induced hypoglycaemia.
Briefly, we discuss the pathophysiology, epidemiology, diagnosis, management and prognosis of these endocrine diseases
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