Uric acid and cardiovascular disease

Authors

  • Joana Guimarães Interna do Internato Complementar de Endocrinologia, Hospitais da Universidade de Coimbra, Coimbra, Portugal
  • Nuno Devesa Interno do Internato Complementar de Medicina Interna, Hospitais da Universidade de Coimbra, Coimbra, Portugal
  • Rita Reis Interna do Internato Complementar de Medicina Interna, Hospitais da Universidade de Coimbra, Coimbra, Portugal
  • Francisco Parente Assistente Graduado de Medicina Interna, Hospitais da Universidade de Coimbra, Coimbra, Portugal
  • Borges Alexandrino Assistente Graduado de Medicina Interna, Hospitais da Universidade de Coimbra, Coimbra, Portugal
  • José Júlio Moura Director do Serviço de Medicina II dos Hospitais da Universidade de Coimbra; Professor da Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal

Keywords:

Uric acid, Cardiovascular Disease, Risk factor

Abstract

The interest in serum uric acid as a potential
Cardiovascular Disease risk factor has balloned in the last several years with numerous
review articles. There seems little doubt that
serum uric acid is a risk factor for Cardiovascular Disease, a perception that has persistfor nearly 50 years. However, the central issue is not whether uric acid is associated with
Cardiovascular Disease, but whether uric acid
plays a causal role in the development of Cardiovascular Disease.
It has been diffi cult to identify the specific
role of elevated serum uric acid because of its
association with established cardiovascular
risk factors such as Hypertension, Diabetes
Mellitus, Hyperlipidaemia and Obesity.
Increased understanding of the mechanisms
underlying these associations may allow a clearer interpretation of the importance of elevated
serum uric acid concentration.

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Additional Files

Published

2004-09-30

How to Cite

1.
Guimarães J, Devesa N, Reis R, Parente F, Alexandrino B, Moura JJ. Uric acid and cardiovascular disease. RPMI [Internet]. 2004 Sep. 30 [cited 2024 Dec. 18];11(3):155-60. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/1759

Issue

Vol. 11 No. 3 (2004): Julho/ Setembro

Section

Review Articles

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