Labial salivary gland biopsy in Sjögren’s syndrome: results and their implications in a population of 78 patients

Authors

  • Tiago Tribolet de Abreu Interno do Internato Complementar de Medicina Interna, Serviço de Medicina 2, Unidade de Doenças Autoimunes do Hospital de Curry Cabral, Lisboa
  • Francisco Soromenho Assistente Graduado de Medicina Interna, Serviço de Medicina 2, Unidade de Doenças Autoimunes do Hospital de Curry Cabral, Lisboa
  • Manuel Vaz Riscado Chefe de Serviço de Medicina Interna, Serviço de Medicina 2, Unidade de Doenças Autoimunes do Hospital de Curry Cabral, Lisboa

Keywords:

Sjögren’s syndrome, classification criteria, labial salivary gland biopsy, Chisholm-Manson classification, European Study Group

Abstract

Objective: To determine:
1) the results of labial salivary gland biopsies (LSGB)
2) the implications of the results with respect to the classification criteria of Sjögren’s syndrome (SS)
3) Assess the sensitivity of LSGB in SS in patients from our Unit with the clinical diagnosis of SS.
Methods: The clinical charts from all the patients with the diagnosis of SS were reviewed using the
European Study Group’s classification criteria.
Results and conclusions: 78 patients had a clinical diagnosis of SS. A LSGB was performed in 56 (71.8%)
patients. According to the Chisholm-Manson classification, the results were: stage 0 (4%), stage 1
(11%), stage 2 (29%), stage 3 (31%) and stage 4 (25%). The LSGB was essential for correct
classification in 44.6% of patients. Its sensitivity was 82.1%, when a stage 3 or 4 was considered.

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Additional Files

Published

2000-12-29

How to Cite

1.
Tribolet de Abreu T, Soromenho F, Vaz Riscado M. Labial salivary gland biopsy in Sjögren’s syndrome: results and their implications in a population of 78 patients. RPMI [Internet]. 2000 Dec. 29 [cited 2024 Dec. 18];7(4):208-12. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/2007

Issue

Vol. 7 No. 4 (2000): Outubro/ Dezembro

Section

Original Articles

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