Unilateral ocular proptosis as the initial manifestation of Wegener’s granulomatosis
DOI:
https://doi.org/10.24950/rspmi.1019Keywords:
Wegener’s granulomatosis, ocular proptosis, orbital massAbstract
Wegener’s granulomatosis (WG), a rare systemic vasculitis of
small and medium caliber vessels, mainly affects the upper and
lower respiratory tract, the ear and the kidney. The occurrence
of orbital and upper airways masses and nasal deformities
caused by destruction of cartilage and bone are suggestive of
WG. Approximately 90% of patients are ANCA positive and the
diagnosis is confirmed through lesions biopsy.
A 77-year-old woman presented left eye proptosis and decreased visual acuity evolving for one month. The MRI revealed
a mass filling the left paranasal sinuses that extended into the
ipsilateral orbital cavity, causing the ocular proptosis. The biopsy revealed a granulomatous inflammatory process that, associated with a positive ANCA, suggested a diagnosis of WG.
Particular emphasis is placed on the unusual form of presentation of WG.
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