Prevalence of recurrent oral ulceration in portuguese general population
Keywords:
Recurrent oral ulceration, oral aphthae, epidemiology, prevalence, PortugalAbstract
Oral aphthae are ulcerous lesions that affect nonkeratinized
mucosae of the mouth cavity, lips, tongue and pharynx. When
these lesions reoccur for three or more episodes per year, are
named as Recurrent Oral Ulceration (ROU). Although recurring
ulcers might be associated with other disorders, ROU usually
expresses a primary problem.
The main objectives of this study were 1) to determine the prevalence of ROU in the general Portuguese population, composed
by people randomly approached without any acute disease; 2) to
compare the observed prevalence with the prevalence of ROU in
other countries and 3) to compare the prevalence of this problem
in patients with other systemic diseases where ROU is included.
A population of six hundred persons was enquired regarding the
age of the disease onset; place of residence, factors triggering
outbreaks, usual treatments and family incidence. Besides, it
was carried out the identification of other diseases associated
with ROU as well as the relevant pathological background. The
prevalence of ROU was 19.0% in this general population, with
predominance of 22.7% in women, compared with 14.0% in men,
being this difference statistically significant (p<0.05). In most of
the affected individuals, the first ulceration appeared before the
twenties. Certain food, oral trauma, stress, fever, menstrual cycle,
presence of acute disease, some medications/drugs and smoking
cessation have been identified as precipitation factors associated
with ROU. In 9.6% of the affected people it was not possible to
identify any cause for recurrent ulcers. We also found that 45.6%
of the population with ROU has direct relatives, up to first degree,
also affected by this problem
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